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What trials pay, and what they cover.

Many trials compensate participants for their time and reimburse the costs of taking part. Here's how it works, what to expect, and how to see it before you apply.

Compensation for your time

Compensation is payment for the time and effort of participating: study visits, questionnaires, blood draws, travel days. It is set by the sponsor, approved by an ethics board, and is the same for everyone in the trial regardless of results.

“Overall, the median clinical trial compensation was US$3070 (range = US$150-US$13,000).”
Fisher JA, McManus L, Kalbaugh JM, Walker RL. Phase I trial compensation: How much do healthy volunteers actually earn from clinical trial enrollment? Clinical Trials. 2021;18(4):477–487. Based on 1,001 Phase I trials that healthy volunteers screened for at 73 research facilities over three years.

Typical US ranges. The exact amount is in each trial's consent form. You are paid for the visits you complete, even if you leave the study early.

Phase 1Healthy volunteersInpatient stays, frequent blood draws, first-in-human dosing$1,500 – $5,500 per study
Phase 1Healthy volunteersOutpatient visits, single or few doses$50 – $150 per visit
Phase 1PatientsDose-finding in serious illness; scans, biopsies$0 – $100 per visit, expenses covered
Phase 2 – 3PatientsRegular visits, labs, imaging, diaries$25 – $100 per visit
Phase 2 – 3Healthy volunteersVaccine or prevention studies; visits and blood draws$50 – $150 per visit
Phase 4 / observationalPatientsSurveys, chart review, occasional visit$0 – $50 per visit
Behavioral / devicePatients or volunteersSessions, wearables, questionnaires$20 – $75 per session

Illustrative ranges, not quotes. Amounts are set per trial and approved by an ethics board; treatment trials for serious conditions often cover expenses only.

Support for taking part

Separate from compensation, many trials cover the practical costs of participating so that distance, work, or family obligations don't keep you out. Study visits, tests, and the study treatment itself are free to you.

Your regular care outside the trial is still billed to you or your insurance as usual. Ask the site which costs the study covers.

Travel reimbursementMileage, tolls, parking, train or airfare to the site. Usually paid back after each visit against receipts, sometimes booked and paid up front.
LodgingA hotel near the site for overnight or multi-day visits, often for a companion too.
TransportationRideshare or car service arranged by the site, or shuttle from nearby lodging.
ChildcareReimbursement for care during visits, or on-site care at some centers.
Virtual visitsSome visits done by video or phone, with labs drawn and treatment given at a local clinic or at home.

Nonprofit programs

Help from outside the trial

Nonprofits that help with the costs of getting to a trial. Funding opens and closes, so check the program's site for current eligibility before you apply.

Travel, lodging and living costs (17)
All cancersAll agesLiving costsTravelLodging
Family Reach – Clinical Trial Access (opens in a new tab)
  • Financial help for people with cancer enrolled in a trial
  • Covers housing, transportation, food and utilities
  • Your oncology social worker applies on your behalf
  • Separate fund for MMRC Horizon myeloma trials
All cancersAdultsLodging
American Cancer Society – Hope Lodge (opens in a new tab)
  • Free lodging for a patient and one caregiver during treatment
  • About 30 locations near US cancer centers
  • Referral from your treatment center; a caregiver must stay with you
All cancersAll agesFlights
Corporate Angel Network (opens in a new tab)
  • Free seats on business jets to cancer treatment and clinical trials
  • No financial-need requirement
  • One companion; patients under 21 may bring two
  • Continental US; must travel without medical help
Childhood cancerChildren & young adultsTravelFlightsLodging
Alex's Lemonade Stand Foundation – Travel For Care (opens in a new tab)
  • Helps pay gas, lodging and airfare to reach treatment
  • For clinical trials or treatment not offered locally
  • Diagnosed by 18 and under 21 when you apply
Childhood cancerChildrenFlightsLodgingRides
Compass to Care – Flights for Hope (opens in a new tab)
  • Airfare, lodging and ground transport to distant trial sites
  • Covers the child and one guardian, continental US
  • Under 18 with active cancer; income limits apply
Childhood cancerChildren & young adultsTravelFlightsLodging
National Children's Cancer Society – Transportation Assistance (opens in a new tab)
  • Mileage, airfare and lodging for cancer treatment travel
  • Diagnosed by 18 and treated before 21
  • Family savings under $5,000; US citizens or residents
Childhood cancerChildrenTravelLodgingMeals
St. Jude Children's Research Hospital (opens in a new tab)
  • Families are never billed for treatment, travel, housing or food
  • Travel for the patient and up to two caregivers
  • For patients accepted at St. Jude
Rare diseasesAll agesTravelLodgingLiving costs
NORD RareCare Patient Assistance (opens in a new tab)
  • Over 100 programs, each for a specific rare disease or study
  • Some cover travel to clinical trials or specialists
  • Others help with medication, tests, premiums and copays
  • Each program opens and closes separately
ALSAdultsTravelLodging
NORD – ALS Travel & Lodging Assistance (opens in a new tab)
  • Helps pay travel to take part in a clinical trial
  • Also covers visits to an ALS specialist
Any conditionChildren & young adultsLodgingMeals
The Children's Inn at NIH (opens in a new tab)
  • Free housing and meals in Bethesda, Maryland
  • For young people in NIH Clinical Center studies and their families
  • Stay as long as the study requires
Any conditionChildrenFlights
Miracle Flights (opens in a new tab)
  • Free commercial flights to medical care in the US
  • Patients 17 and under; up to two parents can fly along
  • Household income up to 370% of the poverty line
Any conditionChildrenFlights
Children's Flight of Hope (opens in a new tab)
  • Free commercial flights to confirmed medical appointments
  • Children through 18, plus one adult companion
  • Based on medical and financial need; request two weeks ahead
Any conditionChildren & young adultsLodgingMeals
Ronald McDonald House Charities (opens in a new tab)
  • Rooms near the hospital for families of children in treatment
  • Free or up to $25 a day; no family turned away
  • Patients 21 and under; each House sets its own rules
Any conditionAll agesRidesFlightsTravel
Mercy Medical Angels (opens in a new tab)
  • Gas cards, ground rides and airline tickets, including to trials
  • Income at or below 300% of the poverty line
  • Trips of 50+ miles by ground or 200+ miles by air
Any conditionAll agesFlights
Air Care Alliance (opens in a new tab)
  • Free flights by volunteer pilots, including to clinical trials
  • One request reaches regional pilot groups
  • Usually within 1,000 miles; most allow a companion
Any conditionAll agesLodging
Healthcare Hospitality Network (opens in a new tab)
  • Directory of hospitality houses near US hospitals
  • Most charge little or nothing
  • Each house sets its own eligibility
Multiple sclerosisAdultsLiving costsRides
National MS Society – MS Navigator (opens in a new tab)
  • Navigators connect you with financial and community resources
  • Short-term help with rent, utilities or rides to appointments

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