What this study is
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
Study details
- Official title
- In Vivo Cardiac Metabolism in Normal, Ischemic, and Cardiomyopathic Patients During Rest and Stress
- Sponsor
- Johns Hopkins University
- Conditions
- Heart Failure, Congestive
- Enrolling
- 500 people
- Starts
- 1988-01
- Est. completion
- 2028-08
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers AcceptedYou may qualify if
- Age > 18 years
- Healthy subjects: no history of heart disease
- Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) <40%
- Left ventricular hypertrophy: wall thickness >1.2cm
- Coronary artery disease: >50% coronary lesion or positive stress test
You can't join if
- Contraindication to MRI
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openJohns Hopkins Medical Institutions
Baltimore, Maryland, United States
- Tricia Steinberg, RN, MSN · Contact443-287-3469asteinb3@jhmi.edu
Recruiting
Study team
Sponsor
Johns Hopkins University
Study ID NA_00044690
Principal investigator
Robert G. Weiss, MD
Johns Hopkins University
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.