What this study is
Dr. Elliott Sherr and his collaborators at University of California, San Francisco (UCSF) are studying the genetic causes of disorders of cognition and epilepsy, in particular disorders of brain development that affect the corpus callosum, such as Aicardi syndrome, as well as two additional brain malformations, polymicrogyria and Dandy-Walker malformation. The goal of the investigators' research is to use a better understanding of the underlying genetic causes as a foundation to develop better treatments for these groups of patients.
Study details
- Official title
- Disorders of Cerebral Development: A Phenotypic and Genetic Analysis
- Sponsor
- University of California, San Francisco
- Conditions
- Brain Disorders · Aicardi Syndrome
- Enrolling
- 2,000 people
- Starts
- 2003-08
- Est. completion
- 2027-01
- Record
- View on ClinicalTrials.gov ↗
Who can join
Sex ALLHealthy volunteers Not acceptedYou may qualify if
- Clinical diagnosis of agenesis or dysgenesis of the corpus callosum, polymicrogyria, or Dandy-Walker malformation
- Should be confirmed by an MRI (Magnetic Resonance Imaging) of the brain
You can't join if
- Fully formed but hypoplastic corpus callosum
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Study locations (1)
1 openUniversity of California, San francisco
San Francisco, California, United States
- Anne Slavotinek, MD · Sub-investigator
- Elysa Marco, MD · Sub-investigator
- Rita J Jeremy, PhD · Sub-investigator
Recruiting
Study team
Sponsor
University of California, San Francisco
Study ID UCSF-PCRC #2206
Principal investigator
Elliott H Sherr, MD, PhD
University of California, San Francisco
Principal investigator
James Barkovich, MD
University of California, San Francisco
Principal investigator
Pratik Mukherjee, MD, PhD
University of California, San Francisco
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.