What this study is
Magnetic resonance imaging (MRI) is currently one of the standard diagnostic imaging methods used to diagnose tumor stage before treatment in the Radiation Oncology Department. It is also used to check responses to radiation after treatment. However, MRI isn't traditionally used in planning for radiation treatment or in checking treated tumor and tissue changes during radiation treatment. The goal is to find out the possible benefits of MRI imaging techniques in these settings of radiation treatment. The research aims are to study the possibility of using devices with new abilities such as the MR-Linac. The MR-Linac combines a radiation treatment machine with a diagnostic MRI scanner. This device will improve the quality of MRI-guided radiation treatment. The MR-Linac has functions that are currently not available in other combined imaging and radiation delivery devices. The MR-Linac does not provide additional imaging capabilities that are not currently available in other imaging devices.
Participating in this study would NOT change the current treatment plans, this will allow the investigators to use the MRI methods in research and future patient care.
What's being tested
- MRI or CT
Intervention · DEVICE
Participants enrolled on this protocol may undergo multiple MRI or CT examinations periodically over the course of their treatment and follow-up if they are participating in a development project related to tumor response assessment. Volunteers enrolled on this protocol may undergo multiple MRI examinations periodically for studies of reproducibility.
Study details
- Official title
- Development and Evaluation of Imaging Acquisition and Analysis Methods for Optimization of MRI and/or CT in Radiation Oncology Simulation, Treatment Planning, and Response Assessment
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Conditions
- Radiation Therapy
- Enrolling
- 837 people
- Starts
- 2015-04-09
- Est. completion
- 2027-04
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers AcceptedYou may qualify if
- Men and women age 18 or older
You can't join if
- Anyone who would be normally excluded from undergoing an MRI examination as per Memorial Hospital for Cancer and Allied Diseases Screening Questionnaire
- Participants/volunteers with a pacemaker, aneurysm clip or any other condition that would warrant avoidance of a strong magnetic field
- Female participants/volunteers who are pregnant or nursing
- Participants/Volunteers who are unable to comply or complete the MRI exam due to claustrophobia or high levels of anxiety
- Participants/Volunteers from the vulnerable population, as defined by 45 CFR 46.
- Participants at higher risk due to age, frailty, or the emergent nature of their condition.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (7)
7 openContact for every open site
- Nancy Lee, MD · Contact212-639-3341
Memorial Sloan Kettering Basking Ridge (Consent only)
Basking Ridge, New Jersey, United States
RecruitingMemorial Sloan Kettering Monmouth (Consent only)
Middletown, New Jersey, United States
RecruitingMemorial Sloan Kettering Bergen (Consent only )
Montvale, New Jersey, United States
RecruitingMemorial Sloan Kettering Commack (Consent Only)
Commack, New York, United States
RecruitingMemorial Sloan Kettering Westchester (Consent only)
Harrison, New York, United States
RecruitingMemorial Sloan Kettering Cancer Center
New York, New York, United States
- Simon Powell, MD · Contact212-639-6072
- Nancy Lee, MD · Principal investigator
RecruitingMemorial Sloan Kettering Nassau (Consent only)
Uniondale, New York, United States
Recruiting
Study team
Sponsor
Memorial Sloan Kettering Cancer Center
Study ID 15-073
Principal investigator
Nancy Lee, MD
Memorial Sloan Kettering Cancer Center
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.