17 OHPC for better mother and baby outcomes in preterm severe preeclampsia

You may qualify if

• UMMC antepartum patients with preterm PE between 23 0/7ths and 34 0/7ths weeks gestation when initially evaluated
• Willing and able to understand study procedures and to provide informed consent

You can't join if

• >33 weeks gestational age or <23 weeks gestation
• Maternal compromise requiring emergent delivery (ongoing placental abruption, DIC, pulmonary edema).
• Fetal compromise requiring emergent delivery (fetal bradycardia, recurrent late fetal heart rate decelerations, minimal to absent fetal heart rate variability).
• Parameters according to current practice guidelines that exclude a patient from expectant management include the following:; Preterm premature rupture of membranes (PPROM) > 34 weeks gestation;; Platelet count < 100,000/microliter (thrombocytopenia) with evidence of HELLP syndrome;; Persistently abnormal hepatic enzyme concentrations (twice or more upper normal values);; Severe fetal growth restriction (ultrasound-estimated fetal weight less than fifth percentile);; Severe Oligohydramnios (AFI < 5cm); Reversal of end diastolic flow(REDF) in umbilical artery Doppler testing;; Recurrent (> 2 readings > 30 minutes apart) severe hypertension despite antihypertensive therapy;; Eclampsia;; Pulmonary edema;; Abruption placentae;; Nonreassuring fetal status during daily testing (biophysical profile <4/10 and/or recurrent variable or late decelerations);; IUFD