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Developmental Dysplasia of the HipDiagnostics and screeningNewbornChildren's healthDiagnostic testDrugEarly Phase 1

What this study is

This study evaluates the feasibility and utility of contrast-enhanced ultrasound to provide real-time assessment of blood flow to the femoral head in infants undergoing surgical reduction for developmental dysplasia of the hip.

What's being tested

  • Intraoperative contrast-enhanced ultrasound (CEUS)

    Intervention · DIAGNOSTIC TEST

    An intraoperative CEUS of the dysplastic femoral head will be performed after surgical reduction of the femoral head and during placement of the spica cast.

  • Lumason

    Intervention · DRUG

    Administration of Lumason contrast agent to improve visualization of epiphyseal vascularity in the femoral head.

Study details

Official title
Use of Intraoperative Contrast-enhanced Ultrasound to Evaluate Femoral Head Perfusion in Infants With Developmental Dysplasia of the Hip at the Time of Surgical Reduction
Sponsor
Children's Hospital of Philadelphia
Conditions
Developmental Dysplasia of the Hip
Enrolling
125 people
Starts
2017-05-22
Est. completion
2030-04
Design
Open-label, single group, Early Phase 1
Record
View on ClinicalTrials.gov ↗