What this study is
The investigators will conduct genetic comparisons between Turner Syndrome (TS) patients with and without Bicuspid Aortic Valve (BAV) to identify causative agents of BAV in people with TS.
The investigators will correlate the patterns and prevalence of structural heart defects in TS women with emerging molecular data to identify patients who are at high risk for cardiovascular complications
What's being tested
- Research genetic tests
Intervention · GENETIC
DNA and tissue-based tests: karyotype, copy number variants, genome-wide association studies and induced pluripotent stem cells
Study details
- Sponsor
- The University of Texas Health Science Center, Houston
- Conditions
- Turner Syndrome
- Enrolling
- 200 people
- Starts
- 2015-08-28
- Est. completion
- 2035-01-01
- Record
- View on ClinicalTrials.gov ↗
Who can join
Sex FEMALEHealthy volunteers Not acceptedYou may qualify if
- Diagnosis of Turner Syndrome
You can't join if
- Diagnosis excluding Turner Syndrome
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
Study locations (1)
1 openUniversity of Texas Health Science Center Houston
Houston, Texas, United States
- Jacqueline Jennings · ContactTSRegistry@uth.tmc.edu
- Contact713-500-6704
- Siddharth Prakash, MD, PhD · Sub-investigator
- Michelle Rivera-Davila, MD · Principal investigator
Recruiting
Study team
Sponsor
The University of Texas Health Science Center, Houston
Study ID HSC-MS-15-0120
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.