Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Advanced Lung Non-Small Cell CarcinomaGeneticsCancerProcedureDrugPhase 2

What this study is

This phase II trial studies how well osimertinib works in treating patients with non-small cell lung cancer with EGFR exon 20 insertion mutation that is stage IIIB-IV or has come back after a period of improvement (recurrent). Osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

What's being tested

Biospecimen Collection
Intervention · PROCEDURE
Undergo collection of blood samples
Computed Tomography with Contrast
Intervention · PROCEDURE
Undergo CT with contrast
Echocardiography Test
Intervention · PROCEDURE
Undergo ECHO
Magnetic Resonance Imaging
Intervention · PROCEDURE
Undergo MRI
Multigated Acquisition Scan
Intervention · PROCEDURE
Undergo MUGA
Osimertinib
Intervention · DRUG
Given PO

Study details

Official title: Phase II Study of Osimertinib (AZD9291) in Advanced NSCLC Patients With Exon 20 Insertion Mutations in EGFR
Sponsor: National Cancer Institute (NCI)
Conditions: Advanced Lung Non-Small Cell Carcinoma · Recurrent Lung Non-Small Cell Carcinoma · Stage IIIB Lung Non-Small Cell Cancer AJCC v7 · Stage IV Lung Non-Small Cell Cancer AJCC v7
Enrolling: 46 people
Starts: 2018-04-25
Est. completion: 2027-06-30
Design: Open-label, single group, Phase 2
Record: View on ClinicalTrials.gov ↗

Who can join

Age 18 Years and overSex ALLHealthy volunteers Not accepted

You may qualify if

Participants must have a pathologically-confirmed diagnosis of non-small cell lung cancer (NSCLC)
Participants must have advanced disease - either stage IV disease, stage IIIB disease not amenable to definitive multi-modality therapy, or recurrent disease after a prior diagnosis of stage I-III disease. All staging is via the American Joint Committee on Cancer (AJCC)/International Association for the Study of Lung Cancer (IASLC) 7th edition staging criteria
An EGFR exon 20 insertion mutation must be detected in the tumor tissue. Patients may be enrolled in the study based on an exon 20 insertion EGFR mutation detected by any Clinical Laboratory Improvement Act (CLIA)-certified tissue assay; NOTE: Testing results are to be submitted via Medidata Rave and the study chair or delegate will review the reports
Patients must have measurable disease; baseline measurements and ALL sites of disease must be obtained within 4 weeks to registration
Patients must have previously received at least one line of therapy for their advanced lung cancer; there are no restrictions on the maximum number of prior therapies allowed
Participants must not have previously received osimertinib
Participants must have not previously received therapies targeting PDL1, PD1 or CTLA4 within 6 months (180 days) prior to registration
Age >= 18 years
Eastern Cooperative Oncology Group (ECOG) performance status =< 1
Hemoglobin >= 9.0 g/L (within 4 weeks before registration)
Leukocytes/white blood cells >= 3,000/mcL (within 4 weeks before registration)
Absolute neutrophil count >= 1,500/mcL (within 4 weeks before registration)
Platelets >= 100,000/mcL (within 4 weeks before registration)
Total bilirubin =< 1.5 x upper limit of normal (ULN) if no liver metastases or =< 3 times ULN in the presence of documented Gilbert's syndrome (unconjugated hyperbilirubinemia) or liver metastases (within 4 weeks before registration)
Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 3 x institutional upper limit of normal; for patients with known hepatic metastases AST and/or ALT =< 5 x ULN (within 4 weeks before registration)
Creatinine =< 1.5 x institutional upper limit of normal (within 4 weeks before registration)
Participants may not have clinically active or symptomatic interstitial lung disease or interstitial pneumonitis (i.e., affecting activities of daily living or requiring therapeutic intervention), or a history of clinically significant interstitial lung disease or radiation pneumonitis
Participants may not have had radiation to the lung fields within four weeks (28 days) of starting treatment. For patients receiving palliative radiation to thoracic vertebrae, ribs or other sites where the radiation field includes the lungs, radiation must be completed at least two weeks before starting treatment. For all palliative radiation to all other sites, at least 7 days must have elapsed prior to starting treatment. At least six months (180 days) must have elapsed prior to starting treatment for radiation given with curative intent. Palliative radiotherapy to control symptoms (including gamma knife technique) is permitted. For stereotactic radiosurgery (SRS) to central nervous system (CNS) lesions, osimertinib can be held on the day of radiation only. For palliative radiotherapy (RT) to other sites of disease outside of the thorax osimertinib (osi) should be held for a minimum of 3 days before radiation and 3 days after RT is completed, but the duration of washout can be adjusted at the investigator's discretion with the approval of the study principal investigator (PI). For thoracic radiation, a 7-10 day washout period before the procedure and one week period after procedure before restarting osimertinib is advised to minimize the risk of pneumonitis. All radiotherapy related toxicities should be managed and ideally resolved before restarting osimertinib. Investigators should consider the radiotherapy when assessing causality if there are any localized adverse events (AEs) following the procedure
Participants may not have clinically symptomatic brain metastases, leptomeningeal disease, or spinal cord compression. Patients may be on a stable dose of corticosteroids to control brain metastases if they have been on a stable dose for two weeks (14 days) prior to study treatment and are clinically asymptomatic
Patients must have an ECHO or a nuclear study (MUGA or first pass) within 4 weeks (28 days) prior to registration to treatment and must not have a left ventricular ejection fraction (LVEF) < institutional lower limit of normal (LLN). If the LLN is not defined at a site, the LVEF must be >= 50% for the patient to be eligible
Participants may not have any of the following cardiac criteria:; Mean resting corrected QT interval (QTc) >= 470 msec obtained from 3 electrocardiograms (ECGs) using the screening clinic ECG machine-derived QTc value; No history of QT prolongation associated with other medications that required discontinuation of that medication; Patient must not be receiving any concomitant medications that are known to be associated with Torsades de Pointes; Any clinically important abnormalities in rhythm, conduction or morphology of resting ECG e.g., complete left bundle branch block, third degree heart block, second degree heart block, any factors that increase the risk of QTc prolongation or risk of arrhythmic events such as heart failure, electrolyte abnormalities (including: serum/plasma potassium < LLN; serum/plasma magnesium < LLN; serum/plasma calcium < LLN), congenital long QT syndrome, family history of long QT syndrome or unexplained sudden death under 40 years of age in first degree relatives or any concomitant medication known to prolong the QT interval; Symptomatic heart failure - New York Heart Association (NYHA) grade II-IV
Participants may not have a second, clinically active, cancer. Patients with second cancers which have been treated with curative intent and/or are currently inactive are allowed
Participants may not be receiving any other investigational agents. Patients previously treated with investigational agents must complete a washout period of at least two weeks or five half-lives, whichever is longer, before starting treatment
Participants may not have uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
Patients must have no history of hypersensitivity active or inactive excipients of osimertinib (AZD9291) or drugs with a similar chemical structure or class to osimertinib (AZD9291)
Patients must not currently be receiving (or unable to stop use prior to receiving the first dose of study treatment) medications or herbal supplements known to be potent inducers of CYP3A4 (at least 3 week prior). All patients must try to avoid concomitant use of any medications, herbal supplements and/or ingestion of foods with known inducer effects on CYP3A4
If medically feasible, patients taking regular medication, with the exception of potent inducers of CYP3A4, should be maintained on it throughout the study period. Patients taking concomitant medications whose disposition is dependent upon breast cancer resistance protein (BCRP) or P-glycoprotein (Pgp) and which have a narrow therapeutic index should be closely monitored for signs of changed tolerability as a result of increased exposure of the concomitant medication whilst receiving osimertinib (AZD9291); NOTE: Use of St John's wort is a contra-indication for osimertinib (AZD9291) use
If applicable, it is recommended that the starting and maintenance dose of rosuvastatin (due to BCRP inhibition by AZD9291 [osimertinib]) should be as low as possible and should be guided by the statin label. Monitoring of low-density lipoprotein (LDL) cholesterol levels is advised. If the subject experiences any potentially relevant adverse events suggestive of muscle toxicity including unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever, the statin should be stopped, creatine kinase (CK) levels should be checked, and any appropriate further management should be taken
Subjects taking warfarin should be monitored regularly for changes in prothrombin time or international normalized ratio (INR)
No unresolved toxicities from prior therapy greater than Common Terminology Criteria for Adverse Events (CTCAE) grade 1 at the time of starting study treatment, with the exception of alopecia and grade 2, prior platinum-therapy-related neuropathy
Patients with refractory nausea and vomiting, chronic gastrointestinal diseases, inability to swallow the formulated product or previous significant bowel resection that would preclude adequate absorption of osimertinib (AZD9291) are ineligible
Women must not be pregnant or breast-feeding because osimertinib (AZD9291) has been shown to cause fetal harm in animal models. All females of childbearing potential must have a blood test or urine study within 2 weeks prior to registration to rule out pregnancy. A female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
Women of childbearing potential (WOCBP) and sexually active males must use an accepted and effective method of contraception while receiving protocol treatment or abstain from sexual intercourse for the duration of their participation in the study. WOCBP must use birth control for two weeks prior to the start of the treatment and continue for 6 weeks after the last dose of the study drug. Sexually active male patients must use effective contraception from day 1 of treatment and continue for 4 months after the last dose of the study drug
Other anticancer agents and investigational agents should not be given while the subject is on study treatment
Supportive care and other medications that are considered necessary for the subject's wellbeing may be given at the discretion of the investigator
A guidance regarding potential interactions with concomitant medications is provided

Study locations (347)

215 open

Fairbanks Memorial Hospital
Fairbanks, Alaska, United States
- Contact907-458-3043 Veronica.Stevenson@foundationhealth.org
- John M. Schallenkamp · Principal investigator
Recruiting
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States
- Contact800-378-9373
- Jay W. Carlson · Principal investigator
Recruiting
CARTI Cancer Center
Little Rock, Arkansas, United States
- Contact501-906-4199 Research@CARTI.com
- Jay W. Carlson · Principal investigator
Recruiting
MedStar Georgetown University Hospital
Washington D.C., District of Columbia, United States
- Contact202-444-2223
- Chul Kim · Principal investigator
Recruiting
Holy Cross Hospital
Fort Lauderdale, Florida, United States
- Contacteileen.georgi@holy-cross.com
- Christopher M. Reynolds · Principal investigator
Recruiting
Emory University Hospital Midtown
Atlanta, Georgia, United States
- Contact888-946-7447
- Ticiana A. Leal · Principal investigator
Recruiting
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States
- Contact404-778-1868
- Ticiana A. Leal · Principal investigator
Recruiting
Emory Saint Joseph's Hospital
Atlanta, Georgia, United States
- Contact404-851-7115
- Ticiana A. Leal · Principal investigator
Recruiting
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States
- Contact734-712-3671 stephanie.couch@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, United States
- Contact734-712-3671 stephanie.couch@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Idaho Urologic Institute-Meridian
Meridian, Idaho, United States
- Contact734-712-3671 stephanie.couch@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
OSF Saint Anthony's Health Center
Alton, Illinois, United States
- Contact618-463-5623
- Jay W. Carlson · Principal investigator
Recruiting
Illinois CancerCare-Bloomington
Bloomington, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Canton
Canton, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Memorial Hospital of Carbondale
Carbondale, Illinois, United States
- Contact618-457-5200 clinical.research@sih.net
- Bryan A. Faller · Principal investigator
Recruiting
SIH Cancer Institute
Carterville, Illinois, United States
- Contact618-985-3333 clinical.research@sih.net
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Carthage
Carthage, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Centralia Oncology Clinic
Centralia, Illinois, United States
- Contact217-876-4762 morganthaler.jodi@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
Carle at The Riverfront
Danville, Illinois, United States
- Contact800-446-5532 Research@Carle.com
- Priyank P. Patel · Principal investigator
Recruiting
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States
- Contact217-876-4762 morganthaler.jodi@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
Decatur Memorial Hospital
Decatur, Illinois, United States
- Contact217-876-4762 morganthaler.jodi@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Dixon
Dixon, Illinois, United States
- Contact815-285-7800
- Bryan A. Faller · Principal investigator
Recruiting
Carle Physician Group-Effingham
Effingham, Illinois, United States
- Contact800-446-5532 Research@carle.com
- Priyank P. Patel · Principal investigator
Recruiting
Crossroads Cancer Center
Effingham, Illinois, United States
- Contact217-876-4762 morganthaler.jodi@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Eureka
Eureka, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Galesburg
Galesburg, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Macomb
Macomb, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, United States
- Contact800-446-5532 Research@carle.com
- Priyank P. Patel · Principal investigator
Recruiting
SSM Health Good Samaritan
Mount Vernon, Illinois, United States
- Contact618-899-1894 gayla.hall@ssmhealth.com
- Jay W. Carlson · Principal investigator
Recruiting
Cancer Care Center of O'Fallon
O'Fallon, Illinois, United States
- Contact217-876-4762 morganthaler.jodi@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois, United States
- Contact217-876-4762 morganthaler.jodi@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Pekin
Pekin, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Peoria
Peoria, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Methodist Medical Center of Illinois
Peoria, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Peru
Peru, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Valley Radiation Oncology
Peru, Illinois, United States
- Contact815-664-4141
- Bryan A. Faller · Principal investigator
Recruiting
Illinois CancerCare-Princeton
Princeton, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Southern Illinois University School of Medicine
Springfield, Illinois, United States
- Contact217-545-7929
- Bryan A. Faller · Principal investigator
Recruiting
Springfield Clinic
Springfield, Illinois, United States
- Contact800-444-7541
- Bryan A. Faller · Principal investigator
Recruiting
Springfield Memorial Hospital
Springfield, Illinois, United States
- Contact217-528-7541 pallante.beth@mhsil.com
- Bryan A. Faller · Principal investigator
Recruiting
Carle Cancer Center
Urbana, Illinois, United States
- Contact800-446-5532 Research@carle.com
- Priyank P. Patel · Principal investigator
Recruiting
The Carle Foundation Hospital
Urbana, Illinois, United States
- Contact800-446-5532 Research@carle.com
- Priyank P. Patel · Principal investigator
Recruiting
Illinois CancerCare - Washington
Washington, Illinois, United States
- Contact309-243-3605 andersonj@illinoiscancercare.com
- Bryan A. Faller · Principal investigator
Recruiting
Central Care Cancer Center - Garden City
Garden City, Kansas, United States
- Contact913-948-5588 aroland@kccop.org
- Jay W. Carlson · Principal investigator
Recruiting
Central Care Cancer Center - Great Bend
Great Bend, Kansas, United States
- Contact913-948-5588 aroland@kccop.org
- Jay W. Carlson · Principal investigator
Recruiting
Mercy Hospital Pittsburg
Pittsburg, Kansas, United States
- Contact888-446-3729
- Jay W. Carlson · Principal investigator
Recruiting
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States
- Contact877-726-5130
- Zofia Piotrowska · Principal investigator
Recruiting
MyMichigan Medical Center Gratiot
Alma, Michigan, United States
- Contact989-631-2469 CVResearch@mymichigan.org
- Christopher M. Reynolds · Principal investigator
Recruiting
MyMichigan Medical Center Alpena
Alpena, Michigan, United States
- Contact989-631-2469 CVResearch@mymichigan.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Bronson Battle Creek
Battle Creek, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health Medical Center - Brighton
Brighton, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health Medical Center - Canton
Canton, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Chelsea Hospital
Chelsea, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Hematology Oncology Consultants-Clarkston
Clarkston, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health IHA Medical Group - Primary Care - Clarkston
Clarkston, Michigan, United States
- Contact248-858-6215 Emily.Crofts@Trinity-Health.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Hospital
Detroit, Michigan, United States
- Contact313-916-3721 CTOResearch@hfhs.org
- Adam M. Forman · Principal investigator
Recruiting
Henry Ford Health Saint John Hospital
Detroit, Michigan, United States
- Contact313-343-3166 Kkeenan1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford River District Hospital
East China Township, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Cancer Hematology Centers - Flint
Flint, Michigan, United States
- Contact810-762-8038 wstrong@ghci.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Genesee Hematology Oncology PC
Flint, Michigan, United States
- Contact810-762-8038 wstrong@ghci.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Genesys Hurley Cancer Institute
Flint, Michigan, United States
- Contact810-762-8038 wstrong@ghci.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Hurley Medical Center
Flint, Michigan, United States
- Contact810-762-8038 wstrong@ghci.org
- Christopher M. Reynolds · Principal investigator
Recruiting
MyMichigan Medical Center Gladwin
Gladwin, Michigan, United States
- Contact989-631-2469 CVResearch@mymichigan.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
Grand Rapids, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods, Michigan, United States
- Contact313-343-3166 karen.forman@ascension.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Bronson Methodist Hospital
Kalamazoo, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
West Michigan Cancer Center
Kalamazoo, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Beacon Kalamazoo Cancer Center
Kalamazoo, Michigan, United States
- Contact574-647-7370
- Kathleen Y. Butler · Principal investigator
Recruiting
Beacon Kalamazoo
Kalamazoo, Michigan, United States
- Contact574-647-7370
- Kathleen Y. Butler · Principal investigator
Recruiting
University of Michigan Health - Sparrow Lansing
Lansing, Michigan, United States
- Contact517-364-3712 harsha.trivedi@umhsparrow.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Saint John Hospital - Macomb Medical
Macomb, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Warren Hospital - Breast Macomb
Macomb, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
MyMichigan Medical Center Midland
Midland, Michigan, United States
- Contact989-631-2469 CVResearch@mymichigan.org
- Christopher M. Reynolds · Principal investigator
Recruiting
MyMichigan Medical Center Mount Pleasant
Mount Pleasant, Michigan, United States
- Contact989-631-2469 CVResearch@mymichigan.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Corewell Health Lakeland Hospitals - Niles Hospital
Niles, Michigan, United States
- Contact616-391-1230
- Kathleen Y. Butler · Principal investigator
Recruiting
Henry Ford Health Providence Novi Hospital
Novi, Michigan, United States
- Contact248-849-5332 kfife3@hfhs.org
- Susan E. Lyons · Principal investigator
Recruiting
Michigan Healthcare Professionals Pontiac
Pontiac, Michigan, United States
- Contact248-858-6215 Emily.Crofts@trinity-health.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health IHA Medical Group-Alice Gustafson Center
Pontiac, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Corewell Health Reed City Hospital
Reed City, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
MyMichigan Medical Center Saginaw
Saginaw, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
Saint Joseph, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Corewell Health Lakeland Hospitals - Saint Joseph Hospital
Saint Joseph, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Henry Ford Health Providence Southfield Hospital
Southfield, Michigan, United States
- Contact248-849-5332 kfife3@hfhs.org
- Susan E. Lyons · Principal investigator
Recruiting
MyMichigan Medical Center Tawas
Tawas City, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Munson Medical Center
Traverse City, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Henry Ford Health Warren Hospital
Warren, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Madison Heights Hospital - Breast
Warren, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Henry Ford Warren Hospital - GLCMS
Warren, Michigan, United States
- Contact313-343-3166 kforman1@hfhs.org
- Christopher M. Reynolds · Principal investigator
Recruiting
University of Michigan Health - West
Wyoming, Michigan, United States
- Contact616-391-1230 crcwm-regulatory@crcwm.org
- Kathleen Y. Butler · Principal investigator
Recruiting
Huron Gastroenterology PC
Ypsilanti, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan, United States
- Contact734-712-7251 MCRCwebsitecontactform@stjoeshealth.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Minnesota Oncology - Burnsville
Burnsville, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Cambridge Medical Center
Cambridge, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Minnesota Oncology Hematology PA-Chaska
Chaska, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Mercy Hospital
Coon Rapids, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Minnesota Oncology - Coon Rapids
Coon Rapids, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Fairview Southdale Hospital
Edina, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Minnesota Oncology - Edina
Edina, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
HealthPartners Cancer Care - Park Nicollet Maple Grove
Maple Grove, Minnesota, United States
- Contact952-883-6000 CancerResearch@HealthPartners.com
- David M. King · Principal investigator
Recruiting
Minnesota Oncology - Maple Grove
Maple Grove, Minnesota, United States
- Contact952-993-1572 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Saint John's Hospital - Healtheast
Maplewood, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Health Partners Inc
Minneapolis, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Monticello Cancer Center
Monticello, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
New Ulm Medical Center
New Ulm, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Fairview Northland Medical Center
Princeton, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
North Memorial Medical Health Center
Robbinsdale, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Regions Hospital
Saint Paul, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
United Hospital
Saint Paul, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Saint Francis Regional Medical Center
Shakopee, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Lakeview Hospital
Stillwater, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Ridgeview Medical Center
Waconia, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Rice Memorial Hospital
Willmar, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Fairview Cancer Center - Woodbury
Woodbury, Minnesota, United States
- Contact651-232-0500 research@fairview.org
- David M. King · Principal investigator
Recruiting
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Fairview Lakes Medical Center
Wyoming, Minnesota, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Mercy Oncology and Hematology - Clayton-Clarkson
Ballwin, Missouri, United States
- Contact888-446-3729
- Jay W. Carlson · Principal investigator
Recruiting
Central Care Cancer Center - Bolivar
Bolivar, Missouri, United States
- Contact913-948-5588 aroland@kccop.org
- Jay W. Carlson · Principal investigator
Recruiting
Cox Cancer Center Branson
Branson, Missouri, United States
- Contact417-269-4520
- Jay W. Carlson · Principal investigator
Recruiting
Mercy Cancer Center - Cape Girardeau
Cape Girardeau, Missouri, United States
- Contact888-446-3729
- Jay W. Carlson · Principal investigator
Recruiting
Saint Francis Medical Center
Cape Girardeau, Missouri, United States
- Contact573-334-2230 sfmc@sfmc.net
- Bryan A. Faller · Principal investigator
Recruiting
Parkland Health Center - Farmington
Farmington, Missouri, United States
- Contact314-996-5569
- Bryan A. Faller · Principal investigator
Recruiting
Freeman Health System
Joplin, Missouri, United States
- Contact417-347-4030 LJCrockett@freemanhealth.com
- Jay W. Carlson · Principal investigator
Recruiting
Mercy Hospital Joplin
Joplin, Missouri, United States
- Contact417-556-3074 esmeralda.carrillo@mercy.net
- Jay W. Carlson · Principal investigator
Recruiting
Lake Regional Hospital
Osage Beach, Missouri, United States
- Contact573-302-2768 clinicaltrials@lakeregional.com
- Jay W. Carlson · Principal investigator
Recruiting
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, United States
- Contact573-458-6379
- Jay W. Carlson · Principal investigator
Recruiting
Phelps Health Delbert Day Cancer Institute
Rolla, Missouri, United States
- Contact573-458-7504 research@phelpshealth.org
- Jay W. Carlson · Principal investigator
Recruiting
Heartland Regional Medical Center
Saint Joseph, Missouri, United States
- Contact816-271-7937 Trisha.England2@mymlc.com
- Jay W. Carlson · Principal investigator
Recruiting
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, United States
- Contact314-996-5569
- Bryan A. Faller · Principal investigator
Recruiting
Mercy Hospital Springfield
Springfield, Missouri, United States
- Contact417-269-4520
- Jay W. Carlson · Principal investigator
Recruiting
CoxHealth South Hospital
Springfield, Missouri, United States
- Contact417-269-4520
- Jay W. Carlson · Principal investigator
Recruiting
Mercy Infusion Center - Chippewa
St Louis, Missouri, United States
- Contact888-446-3729
- Jay W. Carlson · Principal investigator
Recruiting
Mercy Hospital South
St Louis, Missouri, United States
- Contact314-525-6042 Danielle.Werle@mercy.net
- Jay W. Carlson · Principal investigator
Recruiting
Missouri Baptist Medical Center
St Louis, Missouri, United States
- Contact314-996-5569
- Bryan A. Faller · Principal investigator
Recruiting
Mercy Hospital Saint Louis
St Louis, Missouri, United States
- Contact314-251-7066
- Jay W. Carlson · Principal investigator
Recruiting
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, United States
- Contact314-996-5569
- Bryan A. Faller · Principal investigator
Recruiting
Mercy Hospital Washington
Washington, Missouri, United States
- Contact636-390-1600
- Jay W. Carlson · Principal investigator
Recruiting
Community Hospital of Anaconda
Anaconda, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Billings Clinic Cancer Center
Billings, Montana, United States
- Contact800-996-2663 research@billingsclinic.org
- John M. Schallenkamp · Principal investigator
Recruiting
Bozeman Health Deaconess Hospital
Bozeman, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Benefis Sletten Cancer Institute
Great Falls, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Great Falls Clinic
Great Falls, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Hi-Line Sletten Cancer Center
Havre, Montana, United States
- Contactecog.rss@jimmy.harvard.edu
- John M. Schallenkamp · Principal investigator
Recruiting
Benefis Helena Specialty Center
Helena, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Logan Health Medical Center
Kalispell, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
Community Medical Center
Missoula, Montana, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- John M. Schallenkamp · Principal investigator
Recruiting
FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst, North Carolina, United States
- Contact910-715-3500 jcwilliams@firsthealth.org
- Charles S. Kuzma · Principal investigator
Recruiting
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
- Contact800-293-5066 Jamesline@osumc.edu
- Regan M. Memmott · Principal investigator
Recruiting
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
- Contact405-271-8777 ou-clinical-trials@ouhsc.edu
- Raid Aljumaily · Principal investigator
Recruiting
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, United States
- Contact405-752-3402
- Jay W. Carlson · Principal investigator
Recruiting
Saint Alphonsus Cancer Care Center-Baker City
Baker City, Oregon, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Good Samaritan Hospital
Corvallis, Oregon, United States
- Contact541-768-4352 stmock@samhealth.org
- John Strother · Principal investigator
Recruiting
Saint Alphonsus Cancer Care Center-Ontario
Ontario, Oregon, United States
- Contact406-969-6060 mccinfo@mtcancer.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, United States
- Contact610-402-9543 Morgan_M.Horton@lvhn.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, United States
- Contact610-402-9543 Morgan_M.Horton@lvhn.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania, United States
- Contact484-476-2649 turzoe@mlhs.org
- Paul B. Gilman · Principal investigator
Recruiting
Pocono Medical Center
East Stroudsburg, Pennsylvania, United States
- Contact610-402-9543 Morgan_M.Horton@lvhn.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Lehigh Valley Hospital-Hazleton
Hazleton, Pennsylvania, United States
- Contact610-402-9543 Morgan_M.Horton@lvhn.org
- Christopher M. Reynolds · Principal investigator
Recruiting
Riddle Memorial Hospital
Media, Pennsylvania, United States
- Contact484-476-2649 turzoe@mlhs.org
- Paul B. Gilman · Principal investigator
Recruiting
Paoli Memorial Hospital
Paoli, Pennsylvania, United States
- Contact484-476-2649 turzoe@mlhs.org
- Paul B. Gilman · Principal investigator
Recruiting
Lankenau Medical Center
Wynnewood, Pennsylvania, United States
- Contact484-476-2649 turzoe@mlhs.org
- Paul B. Gilman · Principal investigator
Recruiting
University of Virginia Cancer Center
Charlottesville, Virginia, United States
- Contact434-243-6303 uvacancertrials@hscmail.mcc.virginia.edu
- Richard D. Hall · Principal investigator
Recruiting
Fred Hutchinson Cancer Center
Seattle, Washington, United States
- Contact800-804-8824
- Christina S. Baik · Principal investigator
Recruiting
University of Washington Medical Center - Montlake
Seattle, Washington, United States
- Contact800-804-8824
- Christina S. Baik · Principal investigator
Recruiting
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Aurora Saint Luke's South Shore
Cudahy, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Aurora Health Center-Fond du Lac
Fond du Lac, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora Cancer Care-Grafton
Grafton, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora BayCare Medical Center
Green Bay, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, United States
- Contact608-775-2385 cancerctr@gundersenhealth.org
- Kurt Oettel · Principal investigator
Recruiting
Marshfield Medical Center - Ladysmith
Ladysmith, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora Sinai Medical Center
Milwaukee, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Medical Center - Minocqua
Minocqua, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, United States
- Contact952-993-1517 mmcorc@healthpartners.com
- David M. King · Principal investigator
Recruiting
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora Cancer Care-Racine
Racine, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Aurora Medical Center in Summit
Summit, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Clinic-Wausau Center
Wausau, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Aurora West Allis Medical Center
West Allis, Wisconsin, United States
- Contact414-302-2304 ncorp@aurora.org
- Shamsuddin Virani · Principal investigator
Recruiting
Marshfield Medical Center - Weston
Weston, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, United States
- Contact800-782-8581 oncology.clinical.trials@marshfieldresearch.org
- Chady A. Leon · Principal investigator
Recruiting
Memorial Hospital of Laramie County
Cheyenne, Wyoming, United States
- Contactecog.rss@jimmy.harvard.edu
- John M. Schallenkamp · Principal investigator
Recruiting
Billings Clinic-Cody
Cody, Wyoming, United States
- Contact800-996-2663 research@billingsclinic.org
- John M. Schallenkamp · Principal investigator
Recruiting
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, United States
Active, not recruiting
Anchorage Radiation Therapy Center
Anchorage, Alaska, United States
Active, not recruiting
Alaska Breast Care and Surgery LLC
Anchorage, Alaska, United States
Active, not recruiting
Alaska Oncology and Hematology LLC
Anchorage, Alaska, United States
Active, not recruiting
Alaska Women's Cancer Care
Anchorage, Alaska, United States
Active, not recruiting
Anchorage Oncology Centre
Anchorage, Alaska, United States
Active, not recruiting
Katmai Oncology Group
Anchorage, Alaska, United States
Active, not recruiting
Providence Alaska Medical Center
Anchorage, Alaska, United States
Active, not recruiting
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, United States
Active, not recruiting
Saint Luke's Cancer Institute - Boise
Boise, Idaho, United States
Active, not recruiting
Walter Knox Memorial Hospital
Emmett, Idaho, United States
Suspended
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, United States
Active, not recruiting
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, United States
Active, not recruiting
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, United States
Active, not recruiting
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, United States
Active, not recruiting
Rush-Copley Medical Center
Aurora, Illinois, United States
Suspended
Saint Mary's Hospital
Centralia, Illinois, United States
Suspended
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States
Active, not recruiting
Western Illinois Cancer Treatment Center
Galesburg, Illinois, United States
Suspended
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, United States
Active, not recruiting
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, United States
Active, not recruiting
North Shore Medical Center
Skokie, Illinois, United States
Active, not recruiting
Southwest Illinois Health Services LLP
Swansea, Illinois, United States
Suspended
Rush-Copley Healthcare Center
Yorkville, Illinois, United States
Suspended
Midwestern Regional Medical Center
Zion, Illinois, United States
Active, not recruiting
Reid Health
Richmond, Indiana, United States
Active, not recruiting
Heartland Oncology and Hematology LLP
Council Bluffs, Iowa, United States
Active, not recruiting
Methodist Jennie Edmundson Hospital
Council Bluffs, Iowa, United States
Active, not recruiting
Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ
Council Bluffs, Iowa, United States
Active, not recruiting
Iowa Methodist Medical Center
Des Moines, Iowa, United States
Active, not recruiting
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, United States
Active, not recruiting
Broadlawns Medical Center
Des Moines, Iowa, United States
Active, not recruiting
Iowa Lutheran Hospital
Des Moines, Iowa, United States
Active, not recruiting
UI Healthcare Mission Cancer and Blood - Fort Dodge
Fort Dodge, Iowa, United States
Active, not recruiting
Methodist West Hospital
West Des Moines, Iowa, United States
Active, not recruiting
Ochsner Health Center-Summa
Baton Rouge, Louisiana, United States
Active, not recruiting
Medical Center of Baton Rouge
Baton Rouge, Louisiana, United States
Active, not recruiting
Ochsner High Grove
Baton Rouge, Louisiana, United States
Active, not recruiting
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States
Active, not recruiting
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland, United States
Active, not recruiting
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, United States
Active, not recruiting
Brigham and Women's Hospital
Boston, Massachusetts, United States
Suspended
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Suspended
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Suspended
Mercy Medical Center
Springfield, Massachusetts, United States
Active, not recruiting
Caro Cancer Center
Caro, Michigan, United States
Suspended
Newland Medical Associates-Clarkston
Clarkston, Michigan, United States
Suspended
Hope Cancer Clinic
Livonia, Michigan, United States
Suspended
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette, Michigan, United States
Suspended
Trinity Health Muskegon Hospital
Muskegon, Michigan, United States
Suspended
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan, United States
Suspended
Hope Cancer Center
Pontiac, Michigan, United States
Suspended
Henry Ford Rochester Hospital
Rochester Hills, Michigan, United States
Suspended
Oncology Hematology Associates of Saginaw Valley PC
Saginaw, Michigan, United States
Suspended
Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights, Michigan, United States
Suspended
Advanced Breast Care Center PLLC
Warren, Michigan, United States
Suspended
Macomb Hematology Oncology PC
Warren, Michigan, United States
Suspended
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch, Michigan, United States
Suspended
Fairview Ridges Hospital
Burnsville, Minnesota, United States
Suspended
Unity Hospital
Fridley, Minnesota, United States
Active, not recruiting
Parkland Health Center-Bonne Terre
Bonne Terre, Missouri, United States
Suspended
MU Health Care Goldschmidt Cancer Center
Jefferson City, Missouri, United States
Suspended
Saint Peter's Community Hospital
Helena, Montana, United States
Suspended
Saint Patrick Hospital - Community Hospital
Missoula, Montana, United States
Active, not recruiting
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
Omaha, Nebraska, United States
Active, not recruiting
Nebraska Methodist Hospital
Omaha, Nebraska, United States
Active, not recruiting
Oncology Associates PC
Omaha, Nebraska, United States
Suspended
Roswell Park Cancer Institute
Buffalo, New York, United States
Active, not recruiting
Garnet Health Medical Center
Middletown, New York, United States
Suspended
Dickstein Cancer Treatment Center
White Plains, New York, United States
Active, not recruiting
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina, United States
Active, not recruiting
Indu and Raj Soin Medical Center
Beavercreek, Ohio, United States
Active, not recruiting
Saint Elizabeth Boardman Hospital
Boardman, Ohio, United States
Active, not recruiting
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, United States
Active, not recruiting
Miami Valley Hospital South
Centerville, Ohio, United States
Active, not recruiting
Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio, United States
Active, not recruiting
MetroHealth Medical Center
Cleveland, Ohio, United States
Active, not recruiting
Good Samaritan Hospital - Dayton
Dayton, Ohio, United States
Suspended
Miami Valley Hospital
Dayton, Ohio, United States
Active, not recruiting
Dayton Physician LLC - Englewood
Dayton, Ohio, United States
Active, not recruiting
Miami Valley Hospital North
Dayton, Ohio, United States
Active, not recruiting
Armes Family Cancer Center
Findlay, Ohio, United States
Active, not recruiting
Blanchard Valley Hospital
Findlay, Ohio, United States
Active, not recruiting
Orion Cancer Care
Findlay, Ohio, United States
Active, not recruiting
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States
Active, not recruiting
Dayton Physicians LLC-Atrium
Franklin, Ohio, United States
Active, not recruiting
Dayton Physicians LLC-Wayne
Greenville, Ohio, United States
Active, not recruiting
Wayne Hospital
Greenville, Ohio, United States
Active, not recruiting
Greater Dayton Cancer Center
Kettering, Ohio, United States
Active, not recruiting
First Dayton Cancer Care
Kettering, Ohio, United States
Active, not recruiting
Kettering Medical Center
Kettering, Ohio, United States
Active, not recruiting
Springfield Regional Cancer Center
Springfield, Ohio, United States
Active, not recruiting
Springfield Regional Medical Center
Springfield, Ohio, United States
Active, not recruiting
Dayton Physicians LLC - Troy
Troy, Ohio, United States
Active, not recruiting
Upper Valley Medical Center
Troy, Ohio, United States
Active, not recruiting
Saint Joseph Warren Hospital
Warren, Ohio, United States
Active, not recruiting
Saint Elizabeth Youngstown Hospital
Youngstown, Ohio, United States
Active, not recruiting
Saint Charles Health System
Bend, Oregon, United States
Active, not recruiting
Clackamas Radiation Oncology Center
Clackamas, Oregon, United States
Active, not recruiting
Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon, United States
Active, not recruiting
Bay Area Hospital
Coos Bay, Oregon, United States
Active, not recruiting
Providence Newberg Medical Center
Newberg, Oregon, United States
Active, not recruiting
Providence Willamette Falls Medical Center
Oregon City, Oregon, United States
Active, not recruiting
Providence Portland Medical Center
Portland, Oregon, United States
Active, not recruiting
Providence Saint Vincent Medical Center
Portland, Oregon, United States
Active, not recruiting
Saint Charles Health System-Redmond
Redmond, Oregon, United States
Active, not recruiting
Main Line Health Center-Collegeville
Collegeville, Pennsylvania, United States
Suspended
Main Line Health Center-Exton
Exton, Pennsylvania, United States
Suspended
Bryn Mawr Health Center
Newtown Square, Pennsylvania, United States
Suspended
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States
Active, not recruiting
Temple University Hospital
Philadelphia, Pennsylvania, United States
Active, not recruiting
Penn State Health Saint Joseph Medical Center
Reading, Pennsylvania, United States
Suspended
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, United States
Active, not recruiting
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, United States
Active, not recruiting
Providence Regional Cancer System-Centralia
Centralia, Washington, United States
Active, not recruiting
Swedish Cancer Institute-Edmonds
Edmonds, Washington, United States
Active, not recruiting
Providence Regional Cancer Partnership
Everett, Washington, United States
Active, not recruiting
Swedish Cancer Institute-Issaquah
Issaquah, Washington, United States
Active, not recruiting
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, United States
Active, not recruiting
Providence Regional Cancer System-Lacey
Lacey, Washington, United States
Active, not recruiting
PeaceHealth Saint John Medical Center
Longview, Washington, United States
Active, not recruiting
Pacific Gynecology Specialists
Seattle, Washington, United States
Suspended
Swedish Medical Center-Ballard Campus
Seattle, Washington, United States
Active, not recruiting
Kaiser Permanente Washington
Seattle, Washington, United States
Active, not recruiting
Swedish Medical Center-Cherry Hill
Seattle, Washington, United States
Active, not recruiting
Swedish Medical Center-First Hill
Seattle, Washington, United States
Active, not recruiting
PeaceHealth United General Medical Center
Sedro-Woolley, Washington, United States
Active, not recruiting
Providence Regional Cancer System-Shelton
Shelton, Washington, United States
Active, not recruiting
PeaceHealth Southwest Medical Center
Vancouver, Washington, United States
Active, not recruiting
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, United States
Active, not recruiting
Providence Regional Cancer System-Yelm
Yelm, Washington, United States
Active, not recruiting
Welch Cancer Center
Sheridan, Wyoming, United States
Suspended

Osimertinib for advanced lung cancer with an EGFR exon 20 insertion

What this study is

What's being tested

Study details

Who can join

Monitoring & Endpoints

Study locations (347)

Study team

National Cancer Institute (NCI)

Zofia Piotrowska

Frequently asked questions