What this study is
Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.
Study details
- Sponsor
- University of Nebraska
- Conditions
- Rheumatoid Arthritis
- Enrolling
- 125 people
- Starts
- 2017-03-31
- Est. completion
- 2030-03
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 19 Years – 90 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- 19-90 years of age
- Able to give informed consent
- Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years
You can't join if
- Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA)
- Pregnant
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
Study locations (1)
1 openUniversity of Nebraska Medical Center
Omaha, Nebraska, United States
- Bridget Kramer, RN · Contact402-559-4510bridget.kramer@unmc.edu
- Tina A Mahajan, MD · Sub-investigator
- Bryant R England, MD · Principal investigator
Recruiting
Study team
Sponsor
University of Nebraska
Study ID 0282-16-FB
Study chair
Tina D Mahajan, MD
University of Nebraska
Principal investigator
Bryant R England, MD
University of Nebraska
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.