What this study is
This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.
What's being tested
- Biospecimen Collection
Intervention · PROCEDURE
Undergo collection of peripheral blood, bone marrow, and tissue
- Laboratory Biomarker Analysis
Intervention · OTHER
Correlative studies
- Questionnaire Administration
Intervention · OTHER
Ancillary studies
Study details
- Official title
- Protocol for Immunology Specimen Collection From Cancer Patients, Patients With Hematologic Diagnoses, and Healthy Normal Controls
- Sponsor
- University of Southern California
- Conditions
- Healthy Subject · Hematologic and Lymphocytic Disorder · Hematopoietic and Lymphoid Cell Neoplasm · Immune System Disorder · Malignant Neoplasm
- Enrolling
- 625 people
- Starts
- 2017-04-12
- Est. completion
- 2027-12-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 19 Years and overSex ALLHealthy volunteers AcceptedYou may qualify if
- All patients known to have cancer, an immune-mediated hematologic diagnosis, or a healthy normal volunteer
- Definition of immune-mediated hematologic diagnosis: diagnoses for which immune dysfunction and/or immune system directed therapy (eg. aplastic anemia, autoimmune hemolytic anemia, immune thrombocytopenic purpura [ITP], etc.) are involved
- Definition of healthy normal volunteer: persons lacking diagnoses of any type of cancer, diabetes, cardiovascular diseases, non-hematologic autoimmune disease (eg. systemic lupus erythematosus [SLE], rheumatoid arthritis [RA], Crohn's disease) and not taking any immunosuppressive medications
- Patients must have been seen in the Norris Hospital and outpatient clinics, or the Los Angeles County (LAC)-University of Southern California (USC) Medical Center or outpatient clinics; healthy volunteers can be recruited without any physician visit appointments since their labs are strictly for clinical research and not for personal health issues unrelated to the project
You can't join if
- Unable to give informed consent to specimen collection
- Known human immunodeficiency virus (HIV) positive status
- Persons taking any type of immunosuppressive medication are excluded from participating as healthy normal volunteers
- Any patient for whom specimen collection is judged to be unsafe (for example, for patients unable to establish venous access)
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openUSC / Norris Comprehensive Cancer Center
Los Angeles, California, United States
- Arta Zenunovic · Contact323-442-5771Arta.zenunovic@med.usc.edu
- Casey O'Connell, MS · Principal investigator
Recruiting
Study team
Sponsor
University of Southern California
Study ID 0S-15-16
Principal investigator
Casey O'Connell, MD
University of Southern California
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.