What this study is
This protocol is designed as a long-term follow-up study of participants who will receive CAR-T cells as part of a clinical trial at the Medical College of Wisconsin/ Froedtert Hospital. The clinical trials include the following:
Phase 1 Study of CAR-20/19-T Cells in Patients with Relapsed Refractory B Cell Malignancies (NCT03019055); Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma (NCT05976555); CAR20.19.22 T-cells in Relapsed, Refractory B-cell Malignancies (NCT05094206); LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies (NCT05990465); CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies (NCT04186520)
What's being tested
- Long-Term Follow-Up of Participants who Received CAR-T cells
Intervention · OTHER
No study drug is administered in this study. Participants who received CAR-T cells in a previous trial will be evaluated in this trial for long-term safety and efficacy.
Study details
- Sponsor
- Medical College of Wisconsin
- Conditions
- Chronic Lymphocytic Leukemia · Lymphomas Non-Hodgkin's B-Cell · Lymphoma, Small Lymphocytic · Mantle Cell Lymphoma · Central Nervous System Lymphoma · Diffuse Large B Cell Lymphoma · Follicular Lymphoma · Burkitt Lymphoma · Multiple Myeloma
- Enrolling
- 500 people
- Starts
- 2017-12-01
- Est. completion
- 2035-01-01
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 80 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- All participants who enrolled in a CAR-T study at Froedtert Hospital & the Medical College of Wisconsin.
You can't join if
- There are no exclusion criteria for this study.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openFroedtert Hospital & Medical College of Wisconsin
Milwaukee, Wisconsin, United States
- Cancer Center Clinical Trials Office · Contact414-805-8900cccto@mcw.edu
Recruiting
Study team
Sponsor
Medical College of Wisconsin
Study ID PRO30317
Principal investigator
Nirav Shah
Medical College of Wisconsin
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.