What this study is
The Houston Emergency Response Opioid Engagement System (HEROES) is a community-based research program integrating assertive outreach, medication-assisted treatment, behavioral counseling, peer recovery support, and paramedic follow-up in Houston Texas. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder.
What's being tested
- Suboxone
Intervention · DRUG
8mg of buprenorphine/2mg of naloxone
- Brief counseling in the ED
Intervention · BEHAVIORAL
Patients will receive brief counseling from ED physician prior to discharge about the options for outpatient treatment, as well as opioid dependency.Consented patients will be provided with a pamphlet from the Substance Abuse and Mental Health Services Administration called "Facts About Buprenorphine", as well as an information packet for study contact information for the opioid recovery network providers.
- Referral to outpatient treatment
Intervention · BEHAVIORAL
A referral will be made to one of the affiliated MAT clinics.
- Follow-up coaching
Intervention · BEHAVIORAL
A designated paramedic with the Houston Fire Department (called the navigator or care coordinator) will work with UTHealth to jointly follow-up on patients both telephonically and in-person. The Houston Fire Department paramedic will provide brief information sharing and assist with coordination in scheduling or registering with MAT clinics or recovery coaching.
Study details
- Official title
- Houston Emergency Opioid Engagement System (HEROES)
- Sponsor
- The University of Texas Health Science Center, Houston
- Conditions
- Opioid Use Disorder
- Enrolling
- 3,000 people
- Starts
- 2018-04-01
- Est. completion
- 2030-08-31
- Design
- Open-label, single group, Phase 4
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- In otherwise good health based on physician assessment and medical history
- Tests positive in urine sample for opioids
- Patients express a willingness to stop opioid use
- Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence
- Patients must be able to speak English
- Be agreeable to and capable of signing informed consent
You can't join if
- Non-English-speaking patients
- Have a known sensitivity to buprenorphine or naloxone
- Be physiologically dependent on alcohol, benzodiazepines or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.
- Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)
- Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk
- Be a nursing or pregnant female
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openThe University of Texas Health Science Center at Houston
Houston, Texas, United States
Study team
Sponsor
The University of Texas Health Science Center, Houston
Study ID HSC-SBMI-17-1021
Principal investigator
James R Langabeer, EMT, PhD
The University of Texas Health Science Center, Houston
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.