What this study is
Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies.
This is a single-center prospective observational study. The investigators aim to: (1) track critically ill patients undergoing clinically indicated EEG monitoring and seizure management to identify risk factors for electrographic seizures, (2) create prediction models guiding EEG monitoring resources to the patients at highest risk for seizures, and (3) evaluate our current management strategy in terms of safety.
What's being tested
- Clinically indicated EEG monitoring.
Intervention · OTHER
Children enrolled in the study will be undergoing clinically indicated EEG monitoring. Some children will undergo clinically indicated electrographic seizure management.
Study details
- Sponsor
- Children's Hospital of Philadelphia
- Conditions
- Seizures
- Enrolling
- 2,500 people
- Starts
- 2017-03-13
- Est. completion
- 2028-01-01
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 1 Month – 18 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Care in the Children's Hospital of Philadelphia Pediatric ICU.
- Clinically indicated continuous EEG monitoring.
- Age > 1 month to 18 years.
You can't join if
- Admitted for Phase 2 (intracranial) EEG monitoring.
- Intensivist expects to discontinue technological support in the next two days given underlying medical or neurological problems.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openChildren's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
- Nichoals S Abend, MD · Contact215-590-1719
Recruiting
Study team
Sponsor
Children's Hospital of Philadelphia
Study ID 17-013808
Principal investigator
Nicholas S Abend, MD
Children's Hospital of Philadelphia
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.