What this study is
The purpose of the study is to assess precision of the GE Lunar iDXA, Hologic Horizon W DXA scanner, and the Stratec peripheral quantitative computed tomography (pQCT) scanner.
Aim 1: To assess standard deviation (SD) and coefficient of variation (CV) of testing bone mineral, bone geometry, and soft tissues in inanimate objects and adults. Tests on adults will be structured to assess:
1. Within- and between-day variability of testing 2. Within- and between-technician variability of testing 3. Variability due to positioning and post-scan processing 4. Variability due to different DXA scanning equipment
Aim 2: To assess the least significant change (LSC) for testing bone mineral and soft tissues in adults.
Aim 3: To assess strengths and limitations of DXA and pQCT testing, including sensitivity to movement, rate of re-rescanning, etc. which are crucial components for demonstrating feasibility in grant applications.
Aim 4: To construct a database of DXA and pQCT test results and quality control procedures, showing our laboratory's quality control level.
What's being tested
- DXA and pQCT precision testing
Intervention · DEVICE
The participants are only being observed; there is no intervention other than DXA and pQCT testing for the purposes of looking at instrument/technician precision..
Study details
- Official title
- Precision and Reliability of Dual X-ray Absorptiometry (DXA) Testing
- Sponsor
- Penn State University
- Conditions
- Bone and Bones · Body Composition
- Enrolling
- 400 people
- Starts
- 2008-06-16
- Est. completion
- 2028-12-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers AcceptedYou may qualify if
- Healthy adults of two age groups, 1) aged 18-40 or 2) aged >40yr.
You can't join if
- For females, being pregnant
- Having had X-ray procedures using contrast material in the previous 3 days
- Having medical devices that interfere with scan accuracy
- Wearing external metal objects that cannot be removed
- Having internal metal objects
- Body mass of > 450 lbs.
- Having ostomies
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openWomen's Health and Exercise Laboratories, The Pennsylvania State University
University Park, Pennsylvania, United States
- Mary Jane De Souza, PhD · Contact814-863-0045mjd34@psu.edu
- Nancy I Williams, Sc.D. · Sub-investigator
- Mary Jane De Souza, Ph.D. · Principal investigator
Recruiting
Study team
Sponsor
Penn State University
Study ID DXAPrecision
Principal investigator
Mary Jane De Souza, PhD
Penn State
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.