What this study is
Accumulating evidence supports that more pain, whether measured by number of pain sites or pain severity, is associated with poorer cognitive function and mobility, and fall risk in older persons. Tai Chi which holistically integrates physical and cognitive functions offers the possibility not only of alleviating pain but also improving attention and mobility in the many older adults who have chronic multisite pain. This proposed full-size randomized controlled Tai Chi trial is a direct extension of the investigators' previous work examining chronic pain, attention demands, mobility and falls in the older population, and is built on the investigators' National Institute on Aging-supported Tai Chi feasibility and acceptability pilot studies among older adults with multisite pain and risk for falls. The goal of this single-blinded randomized controlled trial is to examine the effects of a 24-week Tai Chi intervention on chronic pain, cognition, mobility, fear of falling, and fall rate in older adults with multisite pain and at risk for falls. The results of this study will provide a foundation to establish the clinical significance of Tai Chi in the management of chronic multisite pain and to explore the mechanisms through which Tai Chi improves chronic pain symptoms and lowers fall rate in at-risk older adults.
What's being tested
- Light physical exercise
Intervention · BEHAVIORAL
One hour each session, two sessions each week, for 6 months. Each session will be structured into three 15-minute segments (including warm-up activities/balance exercise/walking, upper and lower body strength exercise/walking, and stretching exercise/balance exercise/walking, respectively), each ending with a short break to record the Borg Rating of Perceived Exertion (RPE), followed by a 5-minute break time or cool-down/wrap-up session. The session will be taught by a certified exercise physiologist and a research assistant.
- Tai Chi
Intervention · BEHAVIORAL
One hour each session, two sessions each week, for 6 months. Each session will be structured into three 15-minute segments (including warm-up activities/balance exercise/breathing exercise, Tai Chi walking drills, and Tai Chi 8-form, respectively), each ending with a short break to record the RPE, and followed by a 5-minute break or cool-down/wrap-up session. The session will be taught by an experienced Tai Chi instructor and a research assistant.
Study details
- Sponsor
- University of Massachusetts, Boston
- Conditions
- Chronic Pain · Falls
- Enrolling
- 266 people
- Starts
- 2026-10-01
- Est. completion
- 2030-07-31
- Design
- Single-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 65 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Be 65 years or older
- Report chronic multisite (≥2 sites) musculoskeletal pain
- Have had 1 or more falls in the past year or current use of an assistive device (a cane or walker)
- Be able to walk 20 feet without help
- Be able to communicate in English
You can't join if
- Actively engage in moderate to vigorous exercise for more than 40 min/week
- Practiced Tai Chi or other mind-body exercise within the past year, or practiced Tai Chi or other mind-body exercise regularly for at least 3 months within the past 5 years
- Have cognitive impairment consistent with dementia (Montreal Cognitive Assessment (MOCA) score < 18 after corrections),
- Have a diagnosis of a disease/condition that would interfere with their study participation (e.g., rheumatoid arthritis, stroke, Parkinson's disease, degenerative neuromuscular disease, unstable cardiac disease, Alzheimer's disease or other dementia, terminal disease)
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openHELP Study Office and Lab
Boston, Massachusetts, United States
- Tongjian You, PhD · Contact6172875934tongjian.you@umb.edu
- Mekhala Rao, MPH · Contact6172876297mekhala.rao@umb.edu
- Tongjian You, PhD · Principal investigator
Recruiting
Study team
Sponsor
University of Massachusetts, Boston
Study ID 297908
Principal investigator
Tongjian You, PhD
University of Massachusetts, Boston
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.