What this study is
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.
Study details
- Official title
- The Impact of Sinus Surgery in the Era of Highly Effective Modulatory Therapy
- Sponsor
- University of California, Los Angeles
- Conditions
- Chronic Rhinosinusitis (Diagnosis) · Cystic Fibrosis
- Enrolling
- 170 people
- Starts
- 2020-07-01
- Est. completion
- 2027-01-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 99 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old).
- Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride
- Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines
- Chronic rhinosinusitis symptoms persisting beyond initial medical treatment
- Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment
You can't join if
- Underwent endoscopic sinus surgery in past 12 months
- Will obtain follow up care at non-participating institutions
- Unable to complete follow-up surveys
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
Study locations (9)
9 openUniversity of California, Los Angeles
Los Angeles, California, United States
- Marlene Florian · Contactmflorian@mednet.ucla.edu
- Daniel M Beswick, MD · Principal investigator
RecruitingStanford University
Stanford, California, United States
RecruitingUniversity of Colorado
Aurora, Colorado, United States
RecruitingNational Jewish Health
Denver, Colorado, United States
RecruitingUniversity of North Carolina
Chapel Hill, North Carolina, United States
RecruitingOregon Health Science University
Portland, Oregon, United States
RecruitingMedical University of South Carolina
Charleston, South Carolina, United States
RecruitingVanderbilt University Medical Center
Nashville, Tennessee, United States
RecruitingUniversity of Utah
Salt Lake City, Utah, United States
Recruiting
Study team
Sponsor
University of California, Los Angeles
Study ID 20-002079
Principal investigator
Daniel M Beswick, MD
University of California, Los Angeles
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.