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Lung Cancer, Nonsmall CellCancerLungs and breathingDrugPhase 1, Phase 2

What this study is

This is a research study to evaluate the safety and effectiveness of tocilizumab in combination with atezolizumab to treat non-small cell lung cancer.

What's being tested

  • Atezolizumab

    Intervention · DRUG

    1200mg infusion

  • Tocilizumab

    Intervention · DRUG

    Tocilizumab 6mg/kg or 4mg/kg infusion

Study details

Official title
A Phase Ib-II Trial of Tocilizumab and Atezolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy
Sponsor
Abramson Cancer Center at Penn Medicine
Conditions
Lung Cancer, Nonsmall Cell
Enrolling
28 people
Starts
2023-07-25
Est. completion
2027-09
Design
Open-label, single group, Phase 1, Phase 2
Record
View on ClinicalTrials.gov ↗