What this study is
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.
What's being tested
- Diet 1
Intervention · OTHER
- Diet 2
Intervention · OTHER
Both interventions
Dietary intervention
Study details
- Official title
- An Evaluator-blinded Randomized Controlled Trial Study of the Effect of Anti-inflammatory Diet in Subjects With Rheumatoid Arthritis.
- Sponsor
- University of California, San Diego
- Conditions
- Rheumatoid Arthritis
- Enrolling
- 124 people
- Starts
- 2020-11-01
- Est. completion
- 2027-03-01
- Design
- Triple-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Patients with low or moderate disease activity (defined as Clinical Disease Activity Index ≤ 22) and without changes in disease activity or therapy during the previous 3 months, who are interested in dietary intervention, and are able to provide consent and attend to follow up visits.
You can't join if
- Pregnancy or lactating. Patients that will become pregnant during the study will be remove from the study.
- Food allergies
- Subjects with significant other comorbidities and /or medication use which in physician's clinical judgment might difficult the interpretation of the results
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
Study locations (1)
1 openUCSD
La Jolla, California, United States
- Monica Guma, MD · Contactmguma@health.ucsd.edu
- Monica Guma, MD, PhD · Principal investigator
Recruiting
Study team
Sponsor
University of California, San Diego
Study ID 191900
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.