What this study is
The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.
What's being tested
- POWERBreathe Plus®
Intervention · DEVICE
Commercially available pressure-threshold device
- Cardiopulmonary rehabilitation post lung transplant
Intervention · OTHER
Pulmonary function, lung diffusing capacity for carbon monoxide, inspiratory muscle strength, and diaphragm dimensions will be assessed in each patient. Each patient will also undergo a cardiopulmonary exercise test (CPET), 6 minute walk test, and an inspiratory muscle endurance test
Study details
- Official title
- Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant: A Randomized Controlled Trial
- Sponsor
- Mayo Clinic
- Conditions
- Post-Lung Transplantation Bronchiectasis
- Enrolling
- 30 people
- Starts
- 2021-05-10
- Est. completion
- 2027-12
- Design
- Double-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida.
You can't join if
- Patients who do not survive the intra-operative period during the transplant surgery.
- Patients undergoing retransplantation.
- Patients undergoing multiorgan transplantation.
- Patients who are not willing to or who are unable to give written informed consent.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openMayo Clinic in Florida
Jacksonville, Florida, United States
- Temetria Miller · Contact904-953-2000miller.temetria@mayo.edu
Recruiting
Study team
Sponsor
Mayo Clinic
Study ID 20-012778
Principal investigator
Bryan Taylor, PhD
Mayo Clinic
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.