What this study is
The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC). The main questions are
- is POISE feasible to deliver and acceptable to patients
- what is the effect of POISE on the distress patients feel related to their uncertain future, their confidence in their ability to manage cancer, and their understanding about what to expect Participants in the randomized controlled trial will receive either the new supportive care model, POISE, which consists of four visits with a trained palliative care clinician, or care as usual, and will be asked to complete three surveys.
What's being tested
- POISE
Intervention · BEHAVIORAL
POISE (Patient-centered, Optimal Integration of Survivorship and palliative carE) is a brief, population-specific intervention that consists of four sessions with palliative care specialists who have been additionally trained to evaluate and address the specific psychosocial issues and health-promoting behaviors of patients with long, uncertain cancer trajectories.
Study details
- Sponsor
- Massachusetts General Hospital
- Conditions
- Stage IV Non-small Cell Lung Cancer · Targeted Therapy · Nonsmall Cell Lung Cancer · Carcinoma, Non-Small-Cell Lung · ALK-positive Non-small Cell Lung Cancer · EGFR Positive Non-small Cell Lung Cancer · Palliative Care · Survivorship
- Enrolling
- 70 people
- Starts
- 2023-09-29
- Est. completion
- 2027-09-01
- Design
- Single-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Age 18 or older
- MGH Cancer Center patient
- Within 6 months of diagnosis of metastatic NSCLC with oncogenic driver mutation (EGFR, ALK, ROS1, RET)
- Receiving targeted therapy
- Ability to respond in English or Spanish
You can't join if
- Cognitive impairment or serious mental illness that limits ability to provide informed consent
- Need for urgent palliative care or hospice referral
- Pregnant women
- Prisoners
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openMassachusetts General Hospital
Boston, Massachusetts, United States
- Laura A. Petrillo, MD · Contact617-724-4000lpetrillo2@mgh.harvard.edu
- Laura A. Petrillo, MD · Principal investigator
Recruiting
Study team
Sponsor
Massachusetts General Hospital
Study ID 20-722
Principal investigator
Laura A Petrillo, MD
Massachusetts General Hospital
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.