What this study is
Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models.
This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.
What's being tested
- Tissue Collection
Intervention · PROCEDURE
Research tissue specimen will be obtained during the patient's clinical biopsy or clinical tumor resection, if feasible.
- Blood Collection
Intervention · DIAGNOSTIC TEST
Up to 50 mL of research blood will be drawn around the time of the procedure. Additional blood may be collected in selected cases, as warranted, to monitor disease recurrence/remission or perform additional
- Buccal Swab
Intervention · DIAGNOSTIC TEST
Buccal swab may be requested, if necessary, to generate germline data.
Study details
- Sponsor
- Mayo Clinic
- Conditions
- Cancer
- Enrolling
- 50 people
- Starts
- 2022-04-06
- Est. completion
- 2028-03-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- 18 years of age and older
- Patient is a good medical candidate for a standard of care or research biopsy or surgical procedure to obtain tissue
You can't join if
- Uncontrolled concurrent illness including psychiatric illness, or situations that would limit compliance with the study requirements or the ability to willingly give written informed consent
- Institutionalized or incarcerated patients
- Inaccessible tumor for biopsy or patient does not have tumor tissue available for research use
- Biopsy must not be considered more than minimal risk to the patient.
- Have a contraindication to percutaneous biopsy including:; Significant coagulopathy that cannot be adequately corrected.; Severely compromised cardiopulmonary function or hemodynamic instability.; Lack of a safe pathway to the lesion per the interventional radiologist.; Inability of the patient to cooperate with, or to be positioned for, the procedure.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openMayo Clinic in Rochester
Rochester, Minnesota, United States
- Clinical Trials Referral Office · Contact855-776-0015mayocliniccancerstudies@mayo.edu
- Aaron S. Mansfield, M.D. · Principal investigator
Recruiting
Study team
Sponsor
Mayo Clinic
Study ID 21-008831
Principal investigator
Aaron S. Mansfield, M.D.
Mayo Clinic
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.