AutismCognitive functionHealthy volunteersDevice
What this study is
The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.
What's being tested
- Transcranial direct current stimulation
Intervention · DEVICE
TDCS involves applying small (1-2 mA) electric currents to the scalp in order to transiently modify local neuronal electrical potentials in the brain.
Study details
- Sponsor
- American University
- Conditions
- Autism · Autism Spectrum Disorder
- Enrolling
- 80 people
- Starts
- 2022-01-01
- Est. completion
- 2025-12-31
- Design
- Triple-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 35 YearsSex ALLHealthy volunteers AcceptedYou may qualify if
- Please note: This study takes place at American University and Georgetown University in Washington, DC. We do not have funds for travel and lodging available for this study, so participants should be local to the DC region.
- Aged 18-35
- Able to provide written, informed consent
- NIH Toolbox age-adjusted Cognitive Function Composite standard score ≥ 85
- Native English speaker
- Right-handed
- Not pregnant
- Able to attend all study sessions
- Pass safety screening for MRI and neuromodulation (e.g. no metal in body, implanted devices, history of seizure, claustrophobia)
- Prior research-reliable diagnosis of autism spectrum disorder (ASD) Or
- Meet DSM-5 criteria for ASD confirmed with ADOS-2 via research-reliable clinical assessment
You can't join if
- Neurotypical adults
- Age <18 or >35
- NIH Toolbox age-adjusted Cognitive Function Composite standard score < 85
- Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)
- Current or prior history of neurological or neurodevelopmental condition or brain injury
- Psychotropic medication
- Pregnancy Adults with autism
- Age <18 or >35
- Participants with a legal authorized representative
- NIH Toolbox age-adjusted Cognitive Function Composite standard score < 85
- Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)
- Pregnancy
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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1
Study locations (1)
1 openAmerican University
Washington D.C., District of Columbia, United States
- Catherine Stoodley, D.Phil. · Contact202-885-1785stoodley@american.edu
- Catherine Stoodley · Principal investigator
Recruiting
Study team
Sponsor
American University
Study ID R15MH126404
Principal investigator
Kathleen Gunthert, Ph.D.
American University
Have questions? The contacts above can answer them before you apply.
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.