What this study is
This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).
What's being tested
- Cutaneous Probe
Intervention · BEHAVIORAL
A computer-controlled probe delivers temperatures to the skin to measure pain, offset analgesia and onset hyperalgesia.
- Quantitative Sensory Testing
Intervention · BEHAVIORAL
Standard methods involving pinprick, pressure, heat, and cold applied to the skin are used to measure sensation and pain
- Computer Tasks
Intervention · BEHAVIORAL
Quantitative Sensory Testing (QST) and computer tasks are used to measure changes in pain intensity.
Study details
- Official title
- OMEGA Study: Offset Mechanisms in Evaluation of Lumbar Medial Branch Block
- Sponsor
- University of Pittsburgh
- Conditions
- Pain, Chronic · Facet Joint Pain · Pain, Procedural · Analgesia
- Enrolling
- 40 people
- Starts
- 2023-07-05
- Est. completion
- 2028-06
- Design
- Open-label, single group
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Scheduled for lumbar MBB in UPMC Pain Management clinics
- Age > 18 years old
- Predominantly axial chronic low back pain at least 3 months on a daily basis
- Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (>3)
- Low back pain intensity of > 3/10
- Willing and able to receive study-related phone calls
You can't join if
- History of spine surgery at the level of the lumbar MBB
- Active worker's compensation or litigation claims
- New pain and/or psychiatric treatments within 2 weeks of enrollment
- Not fluent in English and/or not able to complete the questionnaires
- Any clinically unstable systemic illness that is judged to interfere with the study
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
Study locations (1)
1 openUPMC St. Margaret
Pittsburgh, Pennsylvania, United States
- Maya L Maurer, BS · Contact412-665-8052mam708@pitt.edu
- Benedict J Alter, MD, PhD · Contact412-677-0575alterbj@upmc.edu
- Benedict J Alter, MD, PhD · Principal investigator
Recruiting
Study team
Sponsor
University of Pittsburgh
Study ID STUDY23040122
Principal investigator
Benedict J Alter, MD, PhD
University of Pittsburgh
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.