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TBI (Traumatic Brain Injury)Exercise and fitnessDigital healthBehavioralBehavioral

What this study is

The purpose of this randomized controlled trial is to evaluate whether the InMotion intervention, delivered via telehealth (using a HIPAA-compliant video platform or phone), which uses evidence-based behavioral and motivational counseling to increase daily physical activity, is an effective treatment for Major Depressive Disorder (MDD) for people who are at least one year out from sustaining a traumatic brain injury (TBI). The first aim is to compare the efficacy of the InMotion intervention to the waitlist control (WLC) condition on measures of depression severity and associated conditions in under-active adults with TBI and MDD. For the second aim the investigators plan to identify possible moderators of exercise treatment effects. The third aim will examine possible mediators of treatment outcome. In addition, the weekly dose of exercise, the extent to which exercise generates positive affect, and engagement in enjoyable or meaningful aspects of life will be explored.

What's being tested

  • InMotion

    Intervention · BEHAVIORAL

    A manualized physical activity counseling program that is based on the Diabetes Prevention Program (DPP) that has been adapted for TBI

Study details

Official title
Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI: A Randomized Controlled Trial (InMotion)
Sponsor
University of Washington
Conditions
TBI (Traumatic Brain Injury) · Depressive Disorder, Major · Clinical Depression · Mood Depressed · Physical Inactivity
Enrolling
80 people
Starts
2023-11-14
Est. completion
2027-09
Design
Single-blind, randomized, parallel groups
Record
View on ClinicalTrials.gov ↗