Type 2 DiabetesNutrition and dietWeight lossChildren's healthMetabolic
What this study is
This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents. The hypothesis of this study is that adolescents at risk for metabolic disease have enhanced MiMo related activities leading to insulin resistance.
Study details
- Official title
- The Role of Circulating Meta-Inflammatory Monocytes in Adolescent Insulin Resistance
- Sponsor
- University of Michigan
- Conditions
- Type 2 Diabetes · Insulin Resistance · Obesity · Metabolic Disease · PreDiabetes
- Enrolling
- 175 people
- Starts
- 2023-09-06
- Est. completion
- 2027-09
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 14 Years – 18 YearsSex ALLHealthy volunteers AcceptedYou may qualify if
- Between 14 and 18 years of age
- Tanner stage 4 or 5 (mature adult stage of puberty)
- Normal weight (BMI ≥ 5th percentile & < 85th percentile), overweight (BMI > 86th percentile) & < 94th percentile), obese weight (BMI percentile ≥ 95th percentile), and/or pre-diabetes (HbA1c > 5.7%)
- For Type 2 Diabetes cohort, diagnosis of Type 2 Diabetes
You can't join if
- Currently pregnant
- Use medications known to affect glucose metabolism (immunosuppressive medications, cancer medications, or high dose steroids), unless prescribed for Type 2 Diabetes management
- Prior diagnosis of autoimmune disease, cancer, or a cognitive or perceptual disability that would inhibit following directions of study staff
- Allergies or intolerance to milk, soy, or palm oil
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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1
Study locations (1)
1 openUniversity of Michigan
Ann Arbor, Michigan, United States
Recruiting
Study team
Sponsor
University of Michigan
Study ID HUM00208301
Principal investigator
Kanakadurga Singer, MA, MD
University of Michigan
Have questions? The contacts above can answer them before you apply.
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.