What this study is
AI INFORM is a multicenter randomized trial that will test the hypothesis that providing clinicians information on the presence and amount of coronary artery calcifications (CAC), will result in initiation or intensification of preventive therapies. The study will use a cloud-based artificial intelligence (AI) platform (Nanox.AI) that can analyze non contrast chest CT and estimate the amount of CAC.
What's being tested
- Electronic health record-based notification of Nanox.AI Coronary Artery Calcification Assessment
Intervention · DEVICE
The intervention involves electronic health record, email, or letter notification about the presence of coronary artery calcification on chest CT and recommendation of preventive therapy. This is based on results of the automatic detection of coronary artery calcification from AI device (software).
Study details
- Official title
- AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention: A Multicenter Randomized Trial
- Sponsor
- Brigham and Women's Hospital
- Conditions
- Coronary Artery Disease
- Enrolling
- 1,500 people
- Starts
- 2024-07-31
- Est. completion
- 2027-12-01
- Design
- Single-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 40 Years – 75 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Patients aged between 40-75 with prior chest CT within last 3 years
You can't join if
- Prior coronary artery disease
- Prior cancer
- Other life-limiting condition
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
Study locations (1)
1 openBrigham and Women's Hospital
Boston, Massachusetts, United States
- Daniel Huck, MD · Contactdhuck@bwh.harvard.edu
- Camila Veronica Souza Freire, MD · Contactcsouzafreire@bwh.harvard.edu
- Daniel Huck, MD · Principal investigator
- Ron Blankstein, MD · Principal investigator
Recruiting
Study team
Sponsor
Brigham and Women's Hospital
Study ID 2023P002954
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.