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Immune Checkpoint TherapyDiagnostics and screeningDiagnostic test

What this study is

To learn if monitoring blood levels of heart injury (troponin levels) in cancer participants treated with immune checkpoint inhibitors will lead to decreased heart-related side effects.

What's being tested

  • Troponin surveillance

    Intervention · DIAGNOSTIC TEST

    Troponin will be monitored prior to each immune checkpoint inhibitor infusion for the first 12 weeks of therapy.

  • Standard of care

    Intervention · OTHER

    Standard of care if symptoms arise then evaluation with cardiac biomarkers and/or further cardiac testing.

Study details

Sponsor
M.D. Anderson Cancer Center
Conditions
Immune Checkpoint Therapy
Enrolling
980 people
Starts
2024-02-02
Est. completion
2028-12-31
Design
Open-label, randomized, single group
Record
View on ClinicalTrials.gov ↗