A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal…

Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)Children's healthDrugPhase 3

What this study is

The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in participants with chronic rhinosinusitis and nasal polyps treated with intranasal corticosteroids. The study will last about 18 months.

What's being tested

LY3650150
Intervention · DRUG
Placebo
Intervention · DRUG
Standard therapy for INCS
Intervention · DRUG
Administered as intranasal spray.

Both LY3650150 and Placebo

Administered SC.

Study details

Official title: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Lebrikizumab/LY3650150 in Participants With Chronic Rhinosinusitis With Nasal Polyps on Background Intranasal Corticosteroids
Sponsor: Eli Lilly and Company
Conditions: Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Enrolling: 510 people
Starts: 2024-04-29
Est. completion: 2028-03
Design: Quadruple-blind, randomized, parallel groups, Phase 3
Record: View on ClinicalTrials.gov ↗

Who can join

Age 12 Years and overSex ALLHealthy volunteers Not accepted

You may qualify if

Physician-diagnosed chronic rhinosinusitis (CRS) with bilateral nasal polyps (NP).
Prior treatment with systemic corticosteroids (SCS) within the last 2 years (or a medical contraindication or intolerance to SCS), prior surgery for NP, or both.
Endoscopic bilateral NPS score of at least 5 out of 8, with a minimum score of 2 in each nasal cavity performed at screening and baseline.
Ongoing symptoms for at least 8 weeks prior to study entry (screening), including:; Nasal congestion with moderate or severe symptom severity (score 2 or 3) at screening and a weekly average severity score of at least 1 (range 0 to 3) at randomization, and; At least one other symptom, such as partial loss of smell (hyposmia), total loss of smell (anosmia), or anterior or posterior rhinorrhea.
Have concomitant asthma must be stable in the 3 months prior to screening using permitted regular asthma treatment.
Adolescent participants ≥12 to <18 years of age and weighing ≥40 kg at time of Visit 1.

You can't join if

Have received a dose of lebrikizumab.
Have received treatment with any rescue medication and/or have the need for surgery for NP during screening and/or run-in period.
Allergen immunotherapy (subcutaneous immunotherapy [SCIT]/sublingual immunotherapy [SLIT]) initiated within 6 months prior to screening, that is not on a stable dose (3 months prior to screening).
Has received a biologic treatment approved for use in CRSwNP, asthma, or AD, even if administered to treat a different condition, within 4 months or 5 half-lives, whichever is longer, prior to screening.
Have received treatment with any biologic or systemic immunosuppressants for inflammatory disease or autoimmune disease prior to the baseline visit:; B cell-depleting biologics, including rituximab, within 6 months.; other biologics within 5 half-lives (if known) or 8 weeks, whichever is longer.; Systemic immunosuppressants within 4 weeks prior to baseline.
Have had any sinus intranasal surgery (including nasal polypectomy) within 6 months prior to screening
Have had prior sino-nasal surgery or sinus surgery changing lateral wall structure of the nose making it difficult to assess endoscopic NPS
Have a presence of any of the following conditions that may impact the assessment of endpoints at screening or baseline:; Nasal septal deviation occluding at least one nostril.; Antrochoanal polyps.; Acute sinusitis, acute nasal infection, or acute upper respiratory infection.; Ongoing rhinitis medicamentosa.; Presence of another diagnosis associated with NP (ie, eosinophilic granulomatosis with polyangiitis, granulomatosis with polyangiitis, Young's syndrome, primary ciliary dyskinesia, cystic fibrosis). Note: for adolescents, documentation for ruling out cystic fibrosis and primary ciliary dyskinesia is required.; A nasal cavity tumor (malignant or benign).; Evidence of fungal rhinosinusitis.
Have anosmia from COVID or any reason other than CRSwNP.
Participants with forced expiratory volume in 1 second (FEV1) 50% or less (of predicted normal) at screening.
Female participant who is pregnant, breastfeeding, or is planning to become pregnant, or to breastfeed during the study.

Study locations (202)

202 open

AllerVie Clinical Research
Birmingham, Alabama, United States
- Weily Soong · Principal investigator
Not yet recruiting
University of Alabama at Birmingham
Birmingham, Alabama, United States
- Contact205-934-7191
- Do Yeon Cho · Principal investigator
Recruiting
Medovation Research
Huntsville, Alabama, United States
- Contact256-322-1553
- William McFeely · Principal investigator
Recruiting
Novak Clinical Research - Tucson - North La Cholla Boulevard
Tucson, Arizona, United States
- Contact520-909-2622
- Robert Dean · Principal investigator
Recruiting
Keck Medicine of USC
Arcadia, California, United States
- Kevin Hur · Principal investigator
Not yet recruiting
University of California, Irvine
Irvine, California, United States
- Naveen Bhandarkar · Principal investigator
Recruiting
ADCRC
La Mesa, California, United States
- Contact619-464-3353
- Geoffrey Pitzer · Principal investigator
Recruiting
Ark Clinical Research
Long Beach, California, United States
- Contact562-997-1000
- Kenneth Kim · Principal investigator
Recruiting
DaVinci Research LLC
Roseville, California, United States
- Contact916-374-6730
- Randall Ow · Principal investigator
Recruiting
Breathe Clear Institute
Torrance, California, United States
- Contact310-372-0700
- Steven Davis · Principal investigator
Recruiting
Colorado ENT & Allergy
Colorado Springs, Colorado, United States
- Contact719-867-7804
- Bryan Davis · Principal investigator
Recruiting
Bioresearch Partner-Kendale Lakes
Miami, Florida, United States
- Contact833-489-4968
- Octavio Carreno · Principal investigator
Recruiting
Orlando ENT & Allergy
Orlando, Florida, United States
- Cecelia Damask · Principal investigator
Not yet recruiting
NuLine Clinical Trial Center
Pompano Beach, Florida, United States
- Contact954-280-7701
- Jacqueline DeNobriga · Principal investigator
Not yet recruiting
University of South Florida
Tampa, Florida, United States
- Contact813-631-4024
- Seong Cho · Principal investigator
Recruiting
MJ Research
Tampa, Florida, United States
- Contact813-249-9100
- Mario Gonzalez-Fernandez · Principal investigator
Not yet recruiting
Treasure Valley Medical Research
Boise, Idaho, United States
- Contact208-813-6505
- Neetu Talreja · Principal investigator
Recruiting
Entopy Research LLC
Chicago, Illinois, United States
- Contact312-399-9337
- Pravin Muniyappa · Principal investigator
Recruiting
Chicago ENT
Chicago, Illinois, United States
- Contact773-289-1823
- Kirk Shepard · Principal investigator
Recruiting
EMEDR
Overland Park, Kansas, United States
- Contact918-991-3578
- Steven Ellis · Principal investigator
Recruiting
South Louisiana Ear, Nose, Throat & Facial Plastic Surgery - PPDS
Mandeville, Louisiana, United States
- James Connolly · Principal investigator
Recruiting
Chesapeake Clinical Research, Inc.
White Marsh, Maryland, United States
- Contact410-931-1966 extension 103
- Sudhir Sekhsaria · Principal investigator
Recruiting
Brigham and Women's Hospital
Boston, Massachusetts, United States
- Contact617-732-6410
- Stella Lee · Principal investigator
Recruiting
University of Missouri
Columbia, Missouri, United States
- Contact573-882-7150
- Christine Franzese · Principal investigator
Recruiting
Washington University School of Medicine
St Louis, Missouri, United States
- Contact314-996-0186
- H James Wedner · Principal investigator
Not yet recruiting
Circuit Clinical/Mercer Allergy and Pulmonary Associates
Hamilton, New Jersey, United States
- Contact201-725-9407
- Peter Ricketti · Principal investigator
Not yet recruiting
Madison ENT & Facial Plastic Surgery
New York, New York, United States
- Contact551-655-4979
- Stacey Silvers · Principal investigator
Recruiting
New York Allergy and Sinus Center
New York, New York, United States
- Contact212-686-6321
- Robert Lin · Principal investigator
Recruiting
Equity Medical
The Bronx, New York, United States
- Contact332-264-0155
- Alissa McInerney · Principal investigator
Recruiting
UCMC
Cincinnati, Ohio, United States
- Ahmad Sedaghat · Principal investigator
Not yet recruiting
Optimed Research, LTD
Columbus, Ohio, United States
- Contact614-430-3030
- Donald McNeil · Principal investigator
Recruiting
Charleston ENT
Charleston, South Carolina, United States
- Contact843-793-0274
- Thomas Murphy · Principal investigator
Recruiting
Medical University of South Carolina- Department of Otolaryngology and Head and Neck Surgery
Charleston, South Carolina, United States
- Contact843-792-1356
- Rodney Schlosser · Principal investigator
Not yet recruiting
Alina Clinical Trials
Dallas, Texas, United States
- Contact214-363-1411
- Barbara Baxter · Principal investigator
Recruiting
UT Southwestern Medical Center
Dallas, Texas, United States
- Contact214-633-4608
- Sei Chung · Principal investigator
Not yet recruiting
University of Texas Physicians Department of Otorhinolaryngology Clinc
Houston, Texas, United States
- Contact713-704-4137
- Amber Luong · Principal investigator
Recruiting
Ear Nose and Throat Associates of Texas PA
McKinney, Texas, United States
- Dale Ehmer, Jr. · Principal investigator
Recruiting
Alamo ENT Associates
San Antonio, Texas, United States
- Contact210-545-0404
- Jeffrey Rosenbloom · Principal investigator
Recruiting
Eastern Virginia Medical School
Norfolk, Virginia, United States
- Contact757-388-6238
- Kent Lam · Principal investigator
Recruiting
Richmond Ear Nose and Throat
Richmond, Virginia, United States
- Contact804-622-3768
- Michael Armstrong · Principal investigator
Not yet recruiting
The Medical College of Wisconsin
Milwaukee, Wisconsin, United States
- Contact414-805-3145,414-314-0430
- David Poetker · Principal investigator
Recruiting

161 sites outside the US

CEMLO - Centro de Especialidades Médicas Lobos
Beunos Aires, Argentina
- Contact54 2227419356
- Dabove Fabian Horacio · Principal investigator
Recruiting
Policonsultorio CEPIR
Buenos Aires, Argentina
- Contact2216075432
- Gabriel Garcia · Principal investigator
Recruiting
Fundacion Respirar
Buenos Aires, Argentina
- Contact541170781548 int 130
- Maria De Salvo · Principal investigator
Recruiting
Fundacion CIDEA
Caba, Argentina
- Contact+54 1149615466 ext 1005
- Jorge Máspero · Principal investigator
Recruiting
Centro de Investigaciones Clínicas - IESR - Rosario
Rosario, Argentina
- Contact54 9 341 360 2129
- Matias Ardusso · Principal investigator
Recruiting
Investigaciones en Patologías Respiratorias SRL
San Miguel de Tucumán, Argentina
- Contact54 3815312192
- Ana Maria Stok · Principal investigator
Recruiting
CIMER-Centro Integral de Medicina Respiratoria
San Miguel de Tucumán, Argentina
- Contact54 3816324041
- María Rojas · Principal investigator
Recruiting
Centro Respiratorio Infantil
Santa Fe, Argentina
- Contact54 93424736908
- Gabriel Gattolin · Principal investigator
Recruiting
CARE - Centro de Alergia y Enfermedades Respiratorias
Villa Crespo, Argentina
- Contact54 1165430113
- Melina Verena Heinze · Principal investigator
Recruiting
Pneumocare
Erpent, Belgium
- Contact+32495823443 +32494384578
- Jean-Benoît Martinot · Principal investigator
Recruiting
UZ Gent
Ghent, Belgium
- Contact+32 93322973
- Philippe Gevaert · Principal investigator
Recruiting
Cliniques Universitaires Saint-Luc Avenue Hippocrate 10
Woluwe-Saint-Lambert, Belgium
- Contact+3227643651
- Valerie Hox · Principal investigator
Recruiting
Multiprofile Hospital For Active Treatment Dr Tota Venkova A
Gabrovo, Bulgaria
- Contact+359899619477
- Dimitar Dimitrov · Principal investigator
Recruiting
Medical Center Medconsult Pleven OOD
Pleven, Bulgaria
- Contact+359889897039
- Georgi Nikolov · Principal investigator
Recruiting
Diagnostic-Consultative Centre Ascendent EOOD
Sofia, Bulgaria
- Contact+359 877519494
- Emiliya Yordanova · Principal investigator
Recruiting
Military Medical Academy - Multiprofile Hospital for Active Treatment - Sofia,
Sofia, Bulgaria
- Contact+359899157816
- Ventzislav Tzvetkov · Principal investigator
Not yet recruiting
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna
Sofia, Bulgaria
- Contact+359888867615
- Yulian Rangachev · Principal investigator
Recruiting
Multiprofile Hospital for Active treatment Trakia EOOD
Zagora, Bulgaria
- Contact+359888130652
- Petar Rouev · Principal investigator
Not yet recruiting
St. Joseph's Hospital
Ontario, Canada
- Contact519-933-5483
- Leigh Sowerby · Principal investigator
Recruiting
CSAC
Québec, Canada
- Contact418-780-0881 x 229
- Remi Gagnon · Principal investigator
Recruiting
The Gordon and Leslie Diamond Health Care Centre
Vancouver, Canada
- Contact605-875-8296
- Arif Janjua · Principal investigator
Not yet recruiting
St Paul's Sinus Centre
Vancouver, Canada
- Contact604-806-9462
- Amin Javer · Principal investigator
Recruiting
Peking University Third Hospital
Beijing, China
- Contact15611963579/82265531
- Yan Yan · Principal investigator
Recruiting
Beijing Hospital
Beijing, China
- Contact15001384090
- Yi Yang · Principal investigator
Not yet recruiting
Beijing Tongren Hospital
Beijing, China
- Contact13269208812
- Chengshuo Wang · Principal investigator
Recruiting
The First Affiliated Hospital of Bengbu Medical College
Bengbu, China
- Contact13855282539
- Yuefeng Han · Principal investigator
Not yet recruiting
The Third Xiangya Hospital of Central South University
Changsha, China
- Contact0731-88618931/15974183357
- Guolin Tan · Principal investigator
Recruiting
Sichuan Provincial People's Hospital
Chengdu, China
- Contact028-87776073/18228061516
- Jiangang Fan · Principal investigator
Recruiting
The First People's Hospital of Foshan
Foshan, China
- Contact18038865188
- Qingqing Yu · Principal investigator
Recruiting
The First Affiliated Hospital Of Fujian Medical University
Fuzhou, China
- Contact13799400365
- chang Lin · Principal investigator
Recruiting
Shenzhen Second People's Hospital
Guangdong, China
- Contact18680309468
- Yongtian Lu · Principal investigator
Recruiting
Hainan General Hospital
Haikou, China
- Contact13807688943
- Xin Wei · Principal investigator
Not yet recruiting
Hangzhou First People's Hospital
Hangzhou, China
- Contact15967138168/0571-56007501
- Yong Li · Principal investigator
Recruiting
Huai'an First People's Hospital
Huai'an, China
- Contact15252382626
- Xin Jin · Principal investigator
Recruiting
The First Affiliated Hospital of Nanchang University
Nanchang, China
- Contact+8613407913590
- Jing Ye · Principal investigator
Recruiting
The People's Hospital of Guangxi Zhuang Autonomous Region
Nanning, China
- Contact18776882290
- Shenhong Qu · Principal investigator
Recruiting
Ningbo Medical Center Lihuili Hospital
Ningbo, China
- Contact15058001932
- Zhisen Shen · Principal investigator
Not yet recruiting
The first Affilliated Hospital Shandong First Medical University
Shandong, China
- Contact13685411586
- Fei Han · Principal investigator
Recruiting
Tongji Hospital of Tongji University
Shanghai, China
- Contact661121219
- Shaoqing Yu · Principal investigator
Recruiting
Shengjing Hospital of China Medical University
Shenyang, China
- Contact18940254987/18940254497
- Zhiwei Cao · Principal investigator
Recruiting
The First Hospital of Shanxi Medical University
Taiyuan, China
- Contact13834132096
- Qinna Zhang · Principal investigator
Recruiting
Tianjin People's Hospital
Tianjin, China
- Contact13820004151
- Xiangli Yang · Principal investigator
Recruiting
Tonghua Central Hospital
Tonghua, China
- Contact13180668096
- Yaowu Dong · Principal investigator
Not yet recruiting
The 2nd Affiliated Hospital of Wenzhou Medical University
Wenzhou Avenue, China
- Contact15868710383
- Liyan Ni · Principal investigator
Recruiting
Union Hospital Tongji Medical College Huazhong University of Science and Technology
Wuhan, China
- Contact18971294483/19971138040
- Jianjun Chen · Principal investigator
Recruiting
Renmin Hospital of Wuhan University
Wuhan, China
- Contact18171485631
- Yu Xu · Principal investigator
Recruiting
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, China
- Contact15105212626
- Wen Liu · Principal investigator
Recruiting
First People's Hospital of Yinchuan
Yinchuan, China
- Contact13895671107
- Ruixia Ma · Principal investigator
Recruiting
Aalborg Universitetshospital Medicinerhuset Lungemedicinsk Forskningsenhed
Aalborg, Denmark
- Contact+45 9766 0672
- Ulla Møller Weinreich · Principal investigator
Recruiting
Aarhus University Hospital, Dept. of Ear-Nose-Throat
Aarhus, Denmark
- Contact+4561389346
- Tejs Ehlers Klug · Principal investigator
Recruiting
Bispebjerg Hospital Department of Respiratory Medicine
Copenhagen, Denmark
- Contact+4530914739
- Asger Sverrild · Principal investigator
Not yet recruiting
Sjællands Universitets Hospital
Køge, Denmark
- Contact+45 47 32 96 52
- Preben Homøe · Principal investigator
Recruiting
Department otorhinolaryngology - Head and Neck Surgery, Helsinki Univerity Hospital
Helsinki, Finland
- Contact+358947176610
- Marie Lundberg · Principal investigator
Recruiting
Departmentof Allergy, Skin and Allergy Hospital, Helsinki Univerity Hospital
Helsinki, Finland
- Contact+358947176610
- Annina Lyly · Principal investigator
Recruiting
Charite-Universitatsmedizin Berlin
Berlin, Germany
- Contact+4930450655227
- Heidi Olze · Principal investigator
Recruiting
HNO Zentrum am Kudamm
Berlin, Germany
- Contact030 88774203
- Önder Göktas · Principal investigator
Recruiting
Praxis für HNO und Allergologie
Dresden, Germany
- Contact+491743195510
- Yury Yarin · Principal investigator
Recruiting
Universitätsklinikum Carl Gustav Carus an der TU Dresden
Dresden, Germany
- Contact+4935145813506
- Philipp Nahrath · Principal investigator
Recruiting
IKF Pneumologie
Frankfurt am Main, Germany
- Contact+4969695972580
- Marc Kornmann · Principal investigator
Recruiting
Universitätsklinikum Jena
Jena, Germany
- Contact+49 36 419 32 54 01
- Orlando Guntinas-Lichius · Principal investigator
Not yet recruiting
Universitätsklinikum Schleswig-Holstein
Lübeck, Germany
- Contact+49 451 500 42001
- Anke Leichtle · Principal investigator
Not yet recruiting
HNO Praxis
Sachsen, Germany
- Contact0351 320 10 160
- Udo Schäfer · Principal investigator
Recruiting
Ujpesti Egeszsegugyi Szolgaltato
Budapest, Hungary
- Contact36703810940
- Attila Laszlo Velich · Principal investigator
Recruiting
Komarom-Esztergom Varmegyei Szent Borbala Korhaz
Tatabánya, Hungary
- Contact3664515526
- Irma Lehocz · Principal investigator
Recruiting
AOU Careggi- University of Florence
Florence, Italy
- Contact0557949450
- Alessandra Vultaggio · Principal investigator
Recruiting
Ospedale San Raffaele
Milan, Italy
- Contact+390226435075
- Giulia Danè · Principal investigator
Not yet recruiting
AOU Federico II Via Pansini
Naples, Italy
- Contact+90817462596
- Aikaterini Detoraki · Principal investigator
Recruiting
Azienda Ospedaliera Di Padova
Padova, Italy
- Contact+39 0498212343
- Giancarlo Ottaviano · Principal investigator
Recruiting
Azienda Ospedaliero Universitaria Pisana - Stabilimento Santa Chiara
Pisa, Italy
- Veronica Seccia · Principal investigator
Recruiting
Fondazione Policlinico A. Gemelli IRCCS
Rome, Italy
- Contact+39 06 30156022
- Galli Jacopo · Principal investigator
Recruiting
ASST Brianza - Vimercate Hospital
Vimercate, Italy
- Contact+39 0396654635
- Federico Quarta · Principal investigator
Recruiting
Toyota Memorial Hospital
Aichi, Japan
- Contact81120023812
- Toshiaki Furuta · Principal investigator
Recruiting
Clinic Kashiwanoha
Chiba, Japan
- Contact81120023812
- Yasuko Murakawa · Principal investigator
Recruiting
University of Yamanashi Hospital
Chūō, Japan
- Contact81120023812
- Daiju Sakurai · Principal investigator
Recruiting
University of Fukui Hospital
Fukui, Japan
- Contact81120023812
- Tetsuji Takabayashi · Principal investigator
Recruiting
Saiseikai Fukuoka General Hospital
Fukuoak, Japan
- Contact81120023812
- Tetsuya Koyama · Principal investigator
Recruiting
Matsuda Hospital
Fukuoka, Japan
- Contact81120023812
- Yoshiki Esaki · Principal investigator
Recruiting
Kyushu University Hospital
Fukuoka, Japan
- Contact81120023812
- Ryota Higuchi · Principal investigator
Recruiting
Osaka Habikino Medical Center
Habikino-shi, Japan
- Contact81120023812
- Kayoko Kawashima · Principal investigator
Recruiting
Kansai Medical University Hospital
Hirakata, Japan
- Contact81120023812
- Yoshiki Kobayashi · Principal investigator
Recruiting
Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital
Hokkaido, Japan
- Contact81120023812
- Hiroaki Netsu · Principal investigator
Recruiting
Hyogo Medical University Hospital
Hyōgo, Japan
- Contact81120023812
- Kenzo Tsuzuki · Principal investigator
Recruiting
Takarazuka City Hospital
Hyōgo, Japan
- Contact81120023812
- Takenori Haruna · Principal investigator
Recruiting
Ibaraki Prefectural Central Hospital
Ibaraki, Japan
- Contact81120023812
- Bungo Nishimura · Principal investigator
Recruiting
Kagoshima Kouseiren Hospital
Kagoshima, Japan
- Contact81120023812
- Takao Makise · Principal investigator
Recruiting
Yokohama City Minato Red Cross Hospital
Kanagawa, Japan
- Contact81120023812
- Takahide Taguchi · Principal investigator
Recruiting
Odawara Municipal Hospital
Kanagawa, Japan
- Contact81120023812
- Masako Terasaki · Principal investigator
Recruiting
Tokai University Hospital
Kanagawa, Japan
- Contact81120023812
- Koichiro Wasano · Principal investigator
Recruiting
Kimitsu Chuo Hospital
Kisarazu, Japan
- Contact81120023812
- Naoki Takahashi · Principal investigator
Recruiting
1-8-1, Kishinoura
Kitakyushu, Japan
- Contact81120023812
- Koji Koike · Principal investigator
Recruiting
3-54-2, Kotohirahommachi
Kumamoto, Japan
- Contact81120023812
- Masayuki Karaki · Principal investigator
Recruiting
Kyosai Hospital
Minami-Alps, Japan
- Contact81120023812
- Tomonori Endo · Principal investigator
Recruiting
Tohoku Medical and Pharmaceutical University Hospital
Miyagi, Japan
- Contact81120023812
- Nobuo Ohta · Principal investigator
Recruiting
Ritsuzankai Iida Hospital
Nagano, Japan
- Contact81120023812
- Shigetoshi Horiguchi · Principal investigator
Recruiting
Asahioka, 1-24
Niigata, Japan
- Contact81120023812
- Hisashi Kamada · Principal investigator
Recruiting
Niigata University Medical & Dental Hospital
Niigata, Japan
- Contact81120023812
- Wakasugi Ryo · Principal investigator
Recruiting
Japan Community Health care Organization Osaka Hospital
Osaka, Japan
- Contact81120023812
- Yohei Maeda · Principal investigator
Recruiting
Kansai Electric Power Hospital
Osaka, Japan
- Contact81120023812
- Akihiko Fujita · Principal investigator
Recruiting
Toho University Sakura Medical Center
Sakura, Japan
- Contact81120023812
- Munetaka Ushio · Principal investigator
Recruiting
8-2 Otemachi
Shizuoka, Japan
- Contact81120023812
- Taiji Kawasaki · Principal investigator
Recruiting
Toho University Ohashi Medical Center
Tokyo, Japan
- Contact81120023812
- Mamoru Yoshikawa · Principal investigator
Recruiting
Nihon University Itabashi Hospital
Tokyo, Japan
- Contact81120023812
- Kikuta Shu · Principal investigator
Recruiting
Mie University Hospital
Tsu, Japan
- Contact81120023812
- Ishigami Eisuke · Principal investigator
Recruiting
JCHO Shimonoseki Medical center
Yamaguchi, Japan
- Contact81120023812
- Kuniyoshi Tanaka · Principal investigator
Recruiting
Yamaguchi University Hospital
Yamaguchi, Japan
- Contact81120023812
- Kazuma Sugahara · Principal investigator
Recruiting
Yokohama Minami Kyosai Hospital
Yokohama, Japan
- Contact81120023812
- Ryo Ikoma · Principal investigator
Recruiting
Avenida Independencia
Aguascalientes, Mexico
- Contact(+52) 449-994-9458
- Erika Nayeli Duron Lopez · Principal investigator
Recruiting
Calle Pascual Orozco #2125 col. Magisterial Universidad
Chihuahua City, Mexico
- Contact526142850691/ 526395010490
- Jesus Antonio Lujan Reyes · Principal investigator
Recruiting
Calle Penitenciaria
Guadalajara Jalsico, Mexico
- Contact523338259344 +523338256493
- Ana Guadalupe · Principal investigator
Recruiting
Miguel Hidalgo 2525, Consultorio 2 Urgencias
Nuevo León, Mexico
- Contact+52 811 517 2010
- Victor Samuel Zuñiga Marquez · Principal investigator
Recruiting
Humboldt 302 Col. Centro
Oaxaca City, Mexico
- Contact+52 951 514 7056
- Lorenzo Tobias Avendaño Santiago · Principal investigator
Recruiting
Niepubliczny Zakład Opieki Zdrowotnej E-Vita
Bialystok, Poland
- Contact881225023
- Ewa Michnowska-Tryburska · Principal investigator
Recruiting
Centrum Medyczne Pratia Katowice
Katowice, Poland
- Contact+48 516 339 109
- Santa Vanaga-Besser · Principal investigator
Recruiting
Centrum Medyczne Angelius Provita
Katowice, Poland
- Contact+48 721-210-110
- Tomasz Grzegorzek · Principal investigator
Recruiting
B&R Clinical Sp. z o.o
Kielce, Poland
- Contact+48 695822532
- Marcin Zawadzki · Principal investigator
Recruiting
Centrum Medyczne All-Med
Krakow, Poland
- Contact608 623 715
- Grazyna Pulka · Principal investigator
Recruiting
Centrum Medyczne Promed ul. Olszańska 5G
Krakow, Poland
- Contact602460190
- Piotr Lach · Principal investigator
Recruiting
Specjalistyczny Niepubliczny Zakład Opieki Zdrowotnej Alergologia Plus Ośrodek Diagnostyki
Poznan, Poland
- Contact+48 61 656 21 65
- Michal Springer · Principal investigator
Recruiting
WIM-PIB
Warsaw, Poland
- Contact+48261816279; +48261817019
- Dariusz Jurkiewicz · Principal investigator
Recruiting
Centrum Medyczne Biotamed Morawska Barbara
Wieliczka, Poland
- Contact+48 606 242 877
- Piotr Morawski · Principal investigator
Recruiting
EMC INSTYTUT MEDYCZNY S.A. Przychodnia
Wroclaw, Poland
- Contact+48 698 659 313
- Marita Nittner-Marszalska · Principal investigator
Recruiting
Centrum Medyczne Oporów
Wroclaw, Poland
- Contact+48 71 712 70 77
- Yogen Abelak · Principal investigator
Recruiting
Unidade Local de Saúde de Almada-Seixal, E.P.E.
Almada, Portugal
- Contact+351 212 727 246
- Luis Antunes · Principal investigator
Not yet recruiting
ULS da Região de Aveiro, EPE - Hospital Infante D. Pedro
Aveiro, Portugal
- Contact(+351)911547254 or 93134164
- Maria Luisa Azevedo · Principal investigator
Recruiting
Centro Clínico Académico - Braga (2CA-Braga) (Hospital de Braga)
Braga, Portugal
- Contact+351925822071/+351912490649
- Daniel Miranda · Principal investigator
Recruiting
Unidade Local de Saúde Loures-Odivelas
Loures, Portugal
- Contact+351 219847259
- Luis Rodrigues · Principal investigator
Recruiting
ULS do Algarve, EPE - Hospital de Portimão
Seco Portimao Faro, Portugal
- Contact+351 961 900 354
- Natacha Santos · Principal investigator
Recruiting
Hospital Pedro Hispano
Senhora da Hora, Portugal
- Contact+351 917 316 904
- Miguel Viana · Principal investigator
Recruiting
Centrul Medical Unirea SRL
Brasov, Romania
- Contact754049720
- Catalin Stefan · Principal investigator
Recruiting
Centrul Medical De Diagnostic Si Tratament Ambulator Neomed S.R.L
Brasov, Romania
- Contact+40722872726
- Anemone Sorana Lupescu · Principal investigator
Recruiting
Centrul Medical De Diagnostic Si Tratament Ambulator Neomed S.R.L
Brasov, Romania
- Contact+40722872726
- Valeriu Bronescu · Principal investigator
Recruiting
Delta Health Care S.R.L
Bucharest, Romania
- Contact0745017816
- Corina Mella · Principal investigator
Recruiting
Delta Health Care S.R.L
Bucharest, Romania
- Contact0722.103.328
- Sorina Dindere · Principal investigator
Recruiting
Cardiomed S.R.L
Cluj-Napoca, Romania
- Contact+40745151216
- Gheorghe Doinel Radeanu · Principal investigator
Recruiting
Centrul de Excelenta in Rinologie S.R.L
Dolj, Romania
- Contact+40 766 409 438
- Mihaela-Roxana Mitroi · Principal investigator
Recruiting
Inje University Haeundae Paik Hospital
Busan, South Korea
- Contact82-51-797-0064
- Yong Wan Kim · Principal investigator
Recruiting
CHA Bundang Medical Center
Gyeonggi-do, South Korea
- Contact82-31-780-3447
- Jae Cheul Ahn · Principal investigator
Recruiting
Pusan National University Hospital
Pusan, South Korea
- Contact82-51-240-7079
- Kyu Sup Cho · Principal investigator
Recruiting
Seoul National University Bundang Hospital
Seongnam-si, South Korea
- Contact+82-31-787-8763
- JEONG WHUN KIM · Principal investigator
Recruiting
Korea University Anam Hospital
Seoul, South Korea
- Contact82-2-920-5362
- Tae Hoon Kim · Principal investigator
Recruiting
SNUH - Seoul National University Hospital
Seoul, South Korea
- Contact82 2 2072 1688
- Dong-Young Kim · Principal investigator
Recruiting
The Catholic University of Korea
Seoul, South Korea
- Contact82-2-2258-2540
- Soo-Whan Kim · Principal investigator
Recruiting
Korea University Guro Hospital
Seoul, South Korea
- Contact82-2-2626-1624
- Heung-Man Lee · Principal investigator
Not yet recruiting
SMG-SNU Boramae Medical Center
Seoul, South Korea
- Contact+8228703928
- Dae Woo Kim · Principal investigator
Recruiting
Ajou University Hospital
Suwon, South Korea
- Contact82-31-219-4252
- Hyun-Jun Kim · Principal investigator
Recruiting
Hospital Universitario Virgen de la Macarena Avenida Dr. Fedriani
Andalucia, Spain
- Contact+34 676366754
- Serafin Sanchez Gomez · Principal investigator
Recruiting
Centro Médico Teknon
Barcelona, Spain
- Contact+34 932906239
- Isam Alobid · Principal investigator
Recruiting
Hospital Universitario de Jerez
Cadiz, Spain
- Contact(+34) 956032505
- Alfonso Del Cuvillo Bernal · Principal investigator
Recruiting
Hospital Clínico Universitario de Santiago
Galícia, Spain
- Contact+34 981950915
- Gabriel Martinez Capoccioni · Principal investigator
Not yet recruiting
FutureMeds DKF
Madrid, Spain
- Contact+34621151370
- Carolina Carrillo · Principal investigator
Recruiting
Hospital Universitario Fundación Jiménez Díaz
Madrid, Spain
- Contact+34915504800 Ext 2374
- Jose Villacampa Auba · Principal investigator
Recruiting
Clinica Universidad de Navarra
Pamplona, Spain
- Contact+34948255400EXT4125
- Gastaminza Gabriel · Principal investigator
Recruiting
Taipei Medical University Shuang Ho Hospital
New Taipei City, Taiwan
- Contact+886-2-22490088 ext:1164
- Cheng-Jung Wu · Principal investigator
Recruiting
National Taiwan University Hospital
Taipei, Taiwan
- Contact+886972652505
- Yi-Tsen Lin · Principal investigator
Recruiting
Bristol Royal Infirmary University Hospitals
Bristol, United Kingdom
- Contact0117 3424175
- Warren Bennett · Principal investigator
Recruiting
Charing Cross Hospital
Chelsea, United Kingdom
- Contact+44(0)2033134333
- Catherina Rennie · Principal investigator
Recruiting
James Paget University Hospitals NHS Foundation Trust
Great Yarmouth, United Kingdom
- Contact01493 453273
- Carl Philpott · Principal investigator
Recruiting
Royal Berkshire NHS Foundation Trust
London, United Kingdom
- Contact0118 3226996
- Robert Almeyda · Principal investigator
Recruiting
Guys and St Thomas' NHS Foundation Trust
London, United Kingdom
- Contact+44 (0)2071888315
- Claire Hopkins · Principal investigator
Recruiting
Newcastle upon Tyne Hospitals NHSFT Freeman Hospital
Newcastle upon Tyne, United Kingdom
- Contact+44 (0)191 2137181 Ext: 37181
- Isma Iqbal · Principal investigator
Recruiting
Stepping Hill Hospital
Stockport, United Kingdom
- Contact0161 419 5818 or 548
- Milan Rudic · Principal investigator
Recruiting

Lebrikizumab for chronic rhinosinusitis with nasal polyps in people aged 12 and older

What this study is

What's being tested

Study details

Who can join

Monitoring & Endpoints

Study locations (202)

Study team

Eli Lilly and Company

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or

Physicians interested in becoming principal investigators please contact

Frequently asked questions