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Colon PolypGut healthProcedure

What this study is

The study will compare the use of cold snare piecemeal resection (CSPR) vs cold endoscopic mucosal resection (Cold EMR). The study will include two cohorts: one cohort for conventional adenomas 10-19mm in size and one cohort for serrated lesions 10mm or larger.

What's being tested

  • Cold Snare Piecemeal Resection (CSPR)

    Intervention · PROCEDURE

    Qualifying polyps randomized to Cold Snare Piecemeal Resection (CSPR) will be removed using cold snare techniques (no electrocautery, no submucosal injection.)

  • Cold Snare Endoscopic Mucosal Resection (Cold EMR)

    Intervention · PROCEDURE

    Qualifying polyps randomized to Cold Snare Endoscopic Mucosal Resection (Cold EMR) will be removed using cold snare techniques (no electrocautery, with submucosal injection.)

Study details

Official title
Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection: A RandomizeD Trial IN Colorectal Adenomas 10-19mm and Serrated Lesions ≥ 10mm (CARDINAL Study)
Sponsor
Indiana University
Conditions
Colon Polyp · Colon Adenoma · Serrated Polyp
Enrolling
570 people
Starts
2024-09-06
Est. completion
2028-07
Design
Open-label, randomized, parallel groups
Record
View on ClinicalTrials.gov ↗