What this study is
The purpose of this study is to compare the efficacy of GentleWave versus EdgePro irrigation in the disinfection of infected root canals of human permanent teeth with necrotic pulp.
What's being tested
- GentleWave
Intervention · DEVICE
Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the GentleWave procedure will be performed
- EdgePro laser irrigation
Intervention · DEVICE
Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the EdgePro procedure will be performed
- Irrisafe passive ultrasonic irrigation
Intervention · DEVICE
Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the passive ultrasonic irrigation procedure will be performed
Study details
- Official title
- Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars: An In-vivo Study
- Sponsor
- The University of Texas Health Science Center, Houston
- Conditions
- Pulp Necroses
- Enrolling
- 30 people
- Starts
- 2024-08-30
- Est. completion
- 2026-04-30
- Design
- Open-label, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Permanent teeth that are diagnosed with pulp necrosis.
- Elected to have a permanent tooth nonsurgical root canal treatment
- Signed informed consent.
You can't join if
- Teeth with root fractures or previously root canal treated teeth.
- Teeth with severe loss of structure
- Teeth with vital pulps.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openThe University of Texas Health Science Center at Houston
Houston, Texas, United States
- David Jaramillo, DDS · Contact(713) 486-4224David.E.Jaramillo@uth.tmc.edu
- Ahmed Shehab-Eldin · Contact9177530852Ahmed.ShehabEldin@uth.tmc.edu
Recruiting
Study team
Sponsor
The University of Texas Health Science Center, Houston
Study ID HSC-DB-24-0062
Principal investigator
David Jaramillo, DDS
The University of Texas Health Science Center, Houston
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.