AgingExercise and fitnessLongevity
What this study is
The purpose of this research is to understand how chronic inflammation affects muscle function and responses to exercise in older adults.
What's being tested
- Exercise
Intervention · OTHER
Young and older adults will perform a single bout of unaccustomed resistance exercise to evaluate molecular and cellular response in skeletal muscle
Study details
- Sponsor
- Mayo Clinic
- Conditions
- Aging
- Enrolling
- 120 people
- Starts
- 2025-01-14
- Est. completion
- 2030-09-16
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 21 Years – 85 YearsSex ALLHealthy volunteers AcceptedYou can't join if
- Diabetes or fasting plasma glucose 126 mg/dL
- Body mass index (BMI) 30 kg/m2
- Anemia (female subjects hemoglobin of <11 g/dl and male subjects hemoglobin <12 g/dl)
- Active coronary artery disease or history of unstable macrovascular disease (unstable angina, myocardial infarction, stroke, and revascularization of coronary, peripheral or carotid artery within 3 months of recruitment)
- Renal failure (serum creatinine > 1.5mg/dl)
- Chronic active liver disease (AST>144IU/L or ALT>165IU/L)
- Oral warfarin group medications or history of blood clotting disorders.
- Smoking
- Pregnancy or breastfeeding
- Alcohol consumption greater than 2 glasses/day or other substance abuse
- Untreated or uncontrolled hypothyroidism
- Debilitating chronic disease (at the discretion of the investigators)
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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1
Study locations (1)
1 openMayo Clinic
Rochester, Minnesota, United States
- Ian R Lanza, PhD · Contact507-255-8147lanza.ian@mayo.edu
- Ian R Lanza, PhD · Principal investigator
Recruiting
Study team
Sponsor
Mayo Clinic
Study ID 24-003329
Principal investigator
Ian Lanza
Mayo Clinic
Have questions? The contacts above can answer them before you apply.
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.