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Iron Deficiency Anemia TreatmentSupplementsNutrition and dietCognitive functionMenopauseWomen's healthDietary supplement

What this study is

The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life. The main questions it aims to answer are:

  • What is the association between iron status, cognitive function, mood, quality of family relationships, and quality of life in perimenopausal women?
  • How does iron repletion, via supplementation, affect cognitive function, mood, quality of family relationships, and quality of life in perimenopausal women?

The investigators will compare the effect of iron supplements to a placebo (gelatin capsule) to see if iron supplements could improve iron status, cognitive function, mood, quality of family relationships, and quality of life of iron-deficient and/or anemic women undergoing the menopausal transition.

Each participant will:

  • Make 2 visits (about 2 hours each - baseline and endline) to the Clinical Research Center at Purdue
  • Make a very brief visit at midpoint (about 10 minutes) for a checkup
  • Take a daily study supplement or placebo for 4 months

What's being tested

  • FeoSol Original Iron Supplement Tablets

    Intervention · DIETARY SUPPLEMENT

    325 mg of ferrous sulfate containing 65 mg of elemental iron

  • 21st Century Gelatin Capsules

    Intervention · DIETARY SUPPLEMENT

    600 mg

Study details

Official title
Rough Journey to Menopause: How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
Sponsor
Purdue University
Conditions
Iron Deficiency Anemia Treatment · Iron Deficiency · Iron Deficiency (Without Anemia)
Enrolling
240 people
Starts
2025-03-01
Est. completion
2025-12
Design
Double-blind, randomized, parallel groups
Record
View on ClinicalTrials.gov ↗