IV IgG with Vyjuvek for wound healing in recessive dystrophic epidermolysis bullosa

You may qualify if

• Diagnosis of generalized Recessive dystrophic epidermolysis bullosa (RDEB) demonstrated by COL7A1 mutations.
• Diagnosis of EBA demonstrated by the presence of levels of serum C7 antibodies above the normal ELISA range
• Baseline skin blistering greater than 5% total body surface area
• 1 wound at least 20 cm^2 able to be entirely treated with Vyjuvek weekly
• 1 wound at least 20 cm^2 that has never been treated with Vyjuvek
• Ongoing VYJUVEK treatment.

You can't join if

• History of thrombotic event(s)
• History of cardiac failure
• History of renal failure
• IgA deficiency