Rectal CarcinomaDiagnostics and screeningProcedure
What this study is
This study evaluates whether images taken using a photon counting detector CT scanner (PCD-CT) can determine the growth of rectal cancer as well as, or better than, MRI for the management of patients with rectal cancer.
What's being tested
- PCD-CT
Intervention · PROCEDURE
Participants undergo PCD-CT scan on study
Study details
- Official title
- Pilot Prospective Study of Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal Cancer
- Sponsor
- Mayo Clinic
- Conditions
- Rectal Carcinoma
- Enrolling
- 200 people
- Starts
- 2024-10-07
- Est. completion
- 2026-12-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 99 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Adult patients 18 to 99 years of age
- Patients with proven rectal cancer clinically referred for staging pelvic MRI and contrast-enhanced CT of the abdomen and pelvis (for evaluation of liver and peritoneal disease)
- Endoscopic or imaging report that tumor is 2 cm or larger
- Patients who are able and willing to sign the informed consent
- Negative pregnancy test if subject is of child-bearing age (females of child-bearing potential will be screened for pregnancy using a urine pregnancy test, which will be administered by the unit study coordinator at no cost to the patient)
You can't join if
- Minors less than 18 years old
- Patient unable to provide written informed consent
- Pregnancy
- Estimated Glomerular Filtration Rate (eGFR) ≤ 60
- History of prior moderate or severe contrast reaction including unresponsiveness, severe respiratory distress, convulsions, arrhythmia, cardiopulmonary distress, progressive angioedema, laryngeal edema, dyspnea, bronchospasm, symptomatic tachycardia, symptomatic bradycardia, hypotension, hypertensive crisis
- Any history of premedication prior to iodinated contrast
- Bilateral hip replacement/prosthesis
- Patients that consent to participation but do not undergo their clinically indicated MRI scanning for any reason (e.g., bad IV, infiltration, reaction, change in indication)
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openMayo Clinic in Rochester
Rochester, Minnesota, United States
- Clinical Trials Referral Office · Contact855-776-0015mayocliniccancerstudies@mayo.edu
- Boleyn Andrist · Contact507-538-7752andrist.boleyn@mayo.edu
- Joel G. Fletcher, MD · Principal investigator
Recruiting
Study team
Sponsor
Mayo Clinic
Study ID 24-001797
Principal investigator
Joel G. Fletcher, MD
Mayo Clinic in Rochester
Have questions? The contacts above can answer them before you apply.
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.