What this study is
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization. Lumbar spine muscle is compromised in LBP, and do, and do not, respond to exercise based physical therapy program depending on measurements representing activation capacity of lumbar muscle. Here, we will characterize the neurological and muscle specific features that may contribute to limited activation in an attempt to identify sources of resistance to recovery in patients with chronic disc injury and identify precision rehabilitation approaches for this complex population of individuals.
What's being tested
- Resistance exercise
Intervention · BEHAVIORAL
An acute bout of a 3 minute resistance exercise will be performed using a lumbar extension exercise machine
Study details
- Official title
- The Contributions of Neural Control and Mechanosensation to Rehabilitation Induced Spine Muscle Recovery
- Sponsor
- University of California, San Diego
- Conditions
- Low Back Pain and Core Muscle · Disc Herniation
- Enrolling
- 152 people
- Starts
- 2025-07-01
- Est. completion
- 2030-05-01
- Design
- Open-label, single group
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 60 YearsSex ALLHealthy volunteers AcceptedYou may qualify if
- Surgical group:
- Individuals diagnosed with chronic disc injury (symptoms > 3 months),
- Individuals planning to undergo a spinal surgery to address the diagnosis of chronic disc injury Physical Therapy Group-
- Individuals diagnosed with chronic disc injury (symptoms >3 months),
- Individuals initiating an exercise-based physical therapy program to address the diagnosis of chronic disc injury Healthy Control group -
- Individuals with no history of chronic back pain (interfering pain lasting >3 months) within the past 3 years,
- No significant spinal pathology beyond normal age-related degenerative changes
You can't join if
- Surgery/Physical therapy groups-History of lumbar spine surgery
- Diabetes
- Neuromuscular diseases
- Epilepsy or other seizure disorder -Healthy control group -
- History of lumbar spine surgery
- History of interfering pain lasting >3 months
- Diabetes
- Neuromuscular diseases
- Epilepsy or other seizure disorder
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openUC San Diego
La Jolla, California, United States
Study team
Sponsor
University of California, San Diego
Study ID HD088437-06
Principal investigator
Bahar Shahidi, PT, PhD
UC San Diego
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.