What this study is
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.
Study details
- Official title
- Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography
- Sponsor
- Oregon Health and Science University
- Conditions
- Anterior Uveitis (AU) · Birdshot Chorioretinitis · Behcet Disease · Herpes Simplex Virus · Juvenile Idiopathic Arthritis (JIA) · Spondyloarthritis (SA) · Sarcoidosis · Posterior Vitreous Detachment
- Enrolling
- 125 people
- Starts
- 2024-09-01
- Est. completion
- 2026-12
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 5 Years – 85 YearsSex ALLHealthy volunteers AcceptedYou may qualify if
- Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
- Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
- Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.
You can't join if
- Inability to give informed consent.
- Inability to maintain stable fixation for OCT imaging.
- Inability to commit to required visits to complete the study.
- Pregnancy and breastfeeding.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openCasey Eye Institute - Oregon Health & Science University
Portland, Oregon, United States
Recruiting
Study team
Sponsor
Oregon Health and Science University
Study ID OHSU IRB0008052
Principal investigator
Yan Li, PhD
Oregon Health and Science University
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.