CT ScanDiagnostics and screeningDiagnostic testPhase 2
What this study is
The goal of this clinical trial is to learn if a new computed tomography (CT) lung perfusion imaging method is as effective as standard of care (SOC) CT imaging. The main question it aims to answer is:
- Does the new contrast-free method provide more information about lung perfusion than SOC?
Participants will undergo a 30 minute chest CT.
What's being tested
- CT scan
Intervention · DIAGNOSTIC TEST
Dynamic contrast-free chest CT scan
Study details
- Official title
- Evaluation of Computed Tomography X-ray-Pulsatility Index (CT-XPI)
- Sponsor
- University of Wisconsin, Madison
- Conditions
- CT Scan · Computed Tomography
- Enrolling
- 30 people
- Starts
- 2026-01-26
- Est. completion
- 2026-12
- Design
- Open-label, single group, Phase 2
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Age 18 years or older
- Able to sign and date the informed consent form
- Will undergo a clinically-indicated CT exam of the head, neck, chest, abdomen, pelvis, or extremities
You can't join if
- Pregnant or lactating
- In need of urgent or emergent care
- Have any conditions that, in the opinion of the PI or designee, would interfere with the evaluation of the results or constitute a health hazard for the participant
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
Loading treatment details…
1
Study locations (1)
1 openUniversity of Wisconsin - Madison
Madison, Wisconsin, United States
- Matthew Smith, MD, PhD · Principal investigator
- Timothy Szczykutowicz, PhD · Sub-investigator
Recruiting
Study team
Sponsor
University of Wisconsin, Madison
Study ID 2025-0586
Principal investigator
Matthew Smith, MD, PhD
University of Wisconsin, Madison
Have questions? The contacts above can answer them before you apply.
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.