What this study is
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.
What's being tested
- No Interventions
Intervention · OTHER
No interventions for participants
Study details
- Official title
- Investigating the Role of Follicular Fluid microRNAs in Ovarian Aging and Assisted Reproductive Success
- Sponsor
- University of Central Florida
- Conditions
- Ovarian Aging · In Vitro Fertilisation (IVF) Treatment · InVitro Fertilization · In Vitro Fertilization Outcome
- Enrolling
- 100 people
- Starts
- 2025-09-22
- Est. completion
- 2026-09
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex FEMALEHealthy volunteers Not acceptedYou may qualify if
- Women undergoing IVF treatment due to male factor infertility or nonovarian causes.
- Age groups: younger women <31 years and older women >38 years.
- Regular menstrual cycles.
- Willing and able to provide informed consent.
You can't join if
- Minors (under 18 years) and women aged 32-37 years
- Diagnosis of polycystic ovarian syndrome (PCOS).
- History of recurrent pregnancy loss.
- Presence of endometriosis.
- Diagnosis of ovarian insufficiency.
- Metabolic disorders (e.g., diabetes).
- History of ovarian surgery or chemotherapy.
- Any condition that might impact follicular fluid quality or IVF outcomes.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openUniversity of Central Florida
Orlando, Florida, United States
- Amoy Fraser, PhD, CCRP, PMP · Contact4072668742Amoy.Fraser@ucf.edu
- Britney-Ann Wray, BS, CCRP, CTBS · Contact4072668742britney-ann.wray@ucf.edu
- Michal Masternak, PhD · Principal investigator
Recruiting
Study team
Sponsor
University of Central Florida
Study ID STUDY00008057
Principal investigator
Michal Masternak, PhD
University of Central Florida
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.