What this study is
This study is testing a new way to help people who are unhoused get screened for cervical cancer. Cervical cancer can often be prevented if it is found early. Many people who lack stable housing usually do not receive regular screenings.
Through this project, the investigators will bring screening to community locations in Tucson, Arizona, using a mobile health unit (MHU) from the University of Arizona (UA) and El Rio Health. At these sites, participants will receive easy-to-understand education about cervical cancer, learn how to collect their own sample for human papillomavirus (HPV) testing, and get follow-up care if needed.
The study has two goals:
- First, the investigators will see if this community-based approach helps more people complete cervical cancer screening.
- Second, the investigators will ask participants, clinicians, and outreach staff for their opinions about the program and its practicality and acceptability.
By testing this approach, the investigators hope to find a way to make cervical cancer screening more accessible and effective for unhoused individuals.
What's being tested
- Human papillomavirus Self-collection
Intervention · OTHER
The individual will receive both verbal instruction on self-collection from trained health educators in the mobile health unit, as well as adapted educational materials on human papillomavirus self-collection and information about follow-up care in the case of abnormal results. Individuals will be provided with a safe and private space in the Mobile Health Unit to self-collect.
- Usual Care
Intervention · OTHER
Usual care, will involve reminders about overdue Cervical Cancer screening and support with scheduling clinic appointments for screening, arranging for transportation, and addressing other barriers to attendance
Study details
- Official title
- Human Papillomavirus Self-Sampling Options to Promote Equity (HOPE)
- Sponsor
- University of Arizona
- Conditions
- Uterine Cervical Neoplasms · HPV Testing · Pap Smear
- Enrolling
- 100 people
- Starts
- 2026-08-01
- Est. completion
- 2027-05-31
- Design
- Open-label, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 30 Years – 64 YearsSex FEMALEHealthy volunteers AcceptedYou may qualify if
- Women or transgender men with a cervix
- Ages 30-64 years
- Due for cervical cancer screening:; No Pap test in the past 3 years, or; No human papillomavirus (HPV) test in the past 5 years
- Unhoused or unstably housed
You can't join if
- History of cervical cancer
- HIV positive
- History of total hysterectomy
- Known pregnancy
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openEl Rio Santa Cruz Neighborhood Health
Tucson, Arizona, United States
- Lisa Soltani, MD · Contact520 670 3909lisas@elrio.org
Study team
Sponsor
University of Arizona
Study ID STUDY00007058
Principal investigator
Dan Theodorescu, MD, PhD
University of Arizona
Study chair
Purnima Madhivanan, MBBS, MPH, PhD
University of Arizona
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.