What this study is
This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions). The comparator is another parent-based approach, PES (Parent Education and Support). The study design is a randomized controlled trial with 2 treatment arms and 3 assessment points (pre, post, and follow-up) using questionnaire data and clinical interviews.
What's being tested
- Supportive Parenting for Anxious Childhood Emotions (SPACE)
Intervention · BEHAVIORAL
Parent based treatment delivered by a therapist 12 weekly sessions with parents.
- Parent Educational Support (PES)
Intervention · BEHAVIORAL
Parent Educational Support: 12 weekly sessions with parents
Study details
- Official title
- Testing a Novel Parent-Based Treatment for Adolescent Anxiety Disorders
- Sponsor
- Yale University
- Conditions
- Anxiety Disorder of Adolescence
- Enrolling
- 108 people
- Starts
- 2025-11-01
- Est. completion
- 2028-11
- Design
- Open-label, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 14 Years – 17 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Meet criteria for a primary DSM-5 AD, including separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, specific phobia, panic disorder, and agoraphobia (determined by the ADIS-C/P).
- Cease all other psychosocial treatment, upon consultation with the project staff and service provider.
- Not currently use any psychotropic medication, other than a stable dose (i.e., same dose for a minimum of 6 months prior to enrollment; no changes during course of the study) of a stimulant medication or selective serotonin reuptake inhibitor (SSRI).
- Have an eligible and willing participating parent (see parent exclusions below).
You can't join if
- Adolescent:
- Meet criteria for any DSM-5 disorder more impairing than the most impairing AD (determined by the ADIS-C/P).
- Have any of the following disorders: autism spectrum disorder; intellectual disability; neurocognitive disorders; bipolar disorder; schizophrenia and other psychotic disorders; and alcohol and substance use disorders (determined by the Health History Form and ADIS-C/P).
- Report a suicide attempt in the last 3 months, or current suicide intent and plans (determined by the ASQ).
- Be a victim of past or present undisclosed abuse requiring investigation or ongoing supervision by the Department of Social Services.
- Not have sufficient proficiency with the English language to complete assessments. Parents:; Have any of the following: intellectual disability; neurocognitive disorders; untreated bipolar disorder; untreated schizophrenia and other psychotic disorders; and untreated alcohol and substance use disorders (determined by the Health History Form).; Not be living with the adolescent at least 50% of the time for at least one year prior to enrollment.; Not have sufficient proficiency with the English language to complete assessments and treatment.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openYale Child Study Center
New Haven, Connecticut, United States
- Rebecca Etkin, PhD · Contact203-737-4644anxiety.csc@yale.edu
Recruiting
Study team
Sponsor
Yale University
Study ID 2000040413
Principal investigator
Rebecca Etkin, PhD
Yale University
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.