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Adults With Variability in Their MoodBehavioralDeviceBehavioral

What this study is

Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day

What's being tested

  • Transcranial alternating current stimulation (tACS)

    Intervention · DEVICE

    Transcranial alternating current stimulation (tACS) is a widely used non-invasive brain stimulation method. The concept underlying alternating current is to simulate the naturally occurring rhythmic pattern of electrophysiological activity of the brain, which can be detected by electroencephalography (EEG). It involves the application of electrodes onto the scalp, which deliver sinusoidal alternating electric currents.

  • Neuro/biofeedback

    Intervention · BEHAVIORAL

    Participants will be shown their their brain EEG recordings and parameters from vocal recordings from their "backup" day, and asked to attempt to use behavioral strategies to match the recording

  • Recall

    Intervention · BEHAVIORAL

    Participants will be given their subjective ratings and notes from a journaling interval to use as a target to restore their mood to how they were feeling on the Visit 1 backup day

  • Physiological stimulation

    Intervention · DEVICE

    Facial electrical stimulation, and chest-worn vibroacoustic stimulation will be used to affect facial muscle activity and peripheral physiology to better approximate previously assessed states.

Study details

Official title
Restorative Neurophysiology: Feasibility of "Backup and Restore" Technologies for Brains and Bodies
Sponsor
University of Pittsburgh
Conditions
Adults With Variability in Their Mood
Enrolling
60 people
Starts
2026-01-01
Est. completion
2029-03-01
Design
Open-label, single group
Record
View on ClinicalTrials.gov ↗