Comparing virtual reality cognitive training and word search puzzles for thinking and quality of life in brain cancer survivors

You may qualify if

• Low grade glioma survivors.
• Have mild cognitive impairment (MCI) per MoCA (defined as any score between 18 and 25).
• Completed all cancer treatment for their low-grade glioma (including chemotherapy, immunotherapy, radiation therapy and surgical procedures) and are now >30 days to 24 months from the date of last treatment.
• Age 18 years or older.
• English speaking.
• Able to provide consent without use of a Legally Authorized Representative
• Available to play the VR game or complete word search puzzles once per day for six days per week for four consecutive weeks in their home (per patient self-report).
• Have a reliable phone number by which they can be reached to make arrangement for testing and for follow-up calls.

You can't join if

• History of serious mental or severe psychiatric illnesses (e.g., bi-polar disorder, schizophrenia etc....). a. Note: Anxiety or depression are not exclusionary. 2. History or known neurodegenerative diseases such as Alzheimer's disease, vascular dementia or any other form of advanced neurodegenerative or neuro-cognitive diseases.
• History of drug intoxication/overdose (addiction history). 4. History of acute traumatic brain injury. 5. History of stroke causing a cognitive deficit only. 6. Vision impairments including legal blindness. aExcept: Note: patients with corrected vision (e.g., glasses or contacts) or who are color-blind are eligible.
• Incarcerated at the time of study enrollment. 8. Enrolled in another clinical trial which does not permit co-enrollment. 9. Any medical condition precluding safe use of VR headset and hand control technology, including patients with medical devices, including cardiac pacemakers, hearing aids/cochlear implants and defibrillators.
• History of motion sickness per patient self-report.