What this study is
The overall objective of the planned future clinical trial is to test the investigator's central hypothesis that habitual singing over several weeks, similar to habitual exercise, will lead to sustained and favorable vascular adaptation, thereby lowering cardiovascular disease (CVD) risk. The overall objective of this study is to refine and protocolize the singing interventions and test the feasibility of the future trial design. The investigative team has previously studied solo singing. Collective singing, as in a choir or small group, is associated with a positive sense of social inclusion, well-being, and improved mood, including in older adults.
What's being tested
- group singing (hybrid format)
Intervention · BEHAVIORAL
12-weeks of group singing, combination of in-person and virtual sessions, 3 times weekly
- instructional sing-along video series
Intervention · BEHAVIORAL
12-week solo singing video series done independently, 3 times weekly
Study details
- Official title
- Group Singing (Hybrid Format) or Solo Singing in Older Adults With Coronary Artery Disease: A Feasibility Study
- Sponsor
- Medical College of Wisconsin
- Conditions
- Coronary Artery Disease · Elderly
- Enrolling
- 32 people
- Starts
- 2026-05-11
- Est. completion
- 2028-02
- Design
- Double-blind, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 55 Years – 89 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- History of coronary artery disease (defined as having at least 1 of the following: myocardial infarction, coronary stent, PCI, CABG, coronary stenosis at least 50%, or coronary artery calcification score at least 300 Agatston units)
You can't join if
- Parkinson's disease or tremor
- Upper arm fistula
- Fingernail onychomycosis
- Pregnancy
- Current tobacco use
- Current illicit drug use
- Current excessive alcohol use (defined as more than 14 drinks/week for women, more than 28 drinks/week for men)
- Unstable CAD (active symptoms of chest discomfort)
- Supplemental oxygen use
- More than mild cognitive impairment (as documented in the medical record by patient's treatment teams)
- Inability to follow study procedures
- Non-English speaking
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openMedical College of Wisconsin
Milwaukee, Wisconsin, United States
- Jacquelyn Kulinski, MD, FASPC · Contact414-955-6896jakulinski@mcw.edu
- Ryan Kacala · Contact414-955-6885rkacala@mcw.edu
Recruiting
Study team
Sponsor
Medical College of Wisconsin
Study ID 00056785
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.