What this study is
An open label study to investigate the safety and efficacy of ponesimod in participants with moderate-to-severe chronic plaque psoriasis
What's being tested
- Ponesimod
Intervention · DRUG
Oral Tablet
Study details
- Official title
- A Multicenter, Open Label Study to Investigate the Safety and Efficacy of Ponesimod in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
- Sponsor
- Vanda Pharmaceuticals
- Conditions
- Moderate-to-severe Chronic Plaque Psoriasis
- Enrolling
- 300 people
- Starts
- 2026-02-17
- Est. completion
- 2028-12
- Design
- Open-label, single group, Phase 3
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 65 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Male and female subjects aged 18-65 years, inclusive
- BMI >18 and <40
- Minimum affected BSA of 10%
- PASI score ≥ 12
- PGA ≥ 3
- Diagnosed with moderate-to-severe plaque psoriasis
You can't join if
- Diagnosis of generalized erythrodermic, generalized pustular (von Zumbusch), guttate, or palmoplantar psoriasis
- History of an allergic reaction or known and/or significant sensitivity to study drug
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (10)
10 openVanda Investigational Site
Glendale, Arizona, United States
RecruitingVanda Investigational Site
Fremont, California, United States
RecruitingVanda Investigational Site
Miami, Florida, United States
RecruitingVanda Investigational Site
Indianapolis, Indiana, United States
RecruitingVanda Investigational Site
Portsmouth, New Hampshire, United States
RecruitingVanda Investigational Site
Rochester, New York, United States
RecruitingVanda Investigational Site
Wilmington, North Carolina, United States
RecruitingVanda Investigational Site
San Antonio, Texas, United States
RecruitingVanda Investigational Site
Webster, Texas, United States
RecruitingVanda Investigational Site
Spokane, Washington, United States
Recruiting
Study team
Sponsor
Vanda Pharmaceuticals
Study ID VP-VSP-128-3102
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.