What this study is
The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock (CS). The investigators aim to compare clinical outcomes in CS patients requiring IABC with normal compliance versus low compliance. The study will enroll patients undergoing IABC that are clinically indicated. Baseline hemodynamic measurements will be obtained and then patients would be stratified based on their compliance. Post IABC, serial hemodynamic measurements will be obtained and compared between groups. Patients will continue to be followed longitudinally until the IABC has been discontinued for any reason. The proposed study will yield results that will aid in developing a larger clinical trial and ultimately assist clinicians in determining if IABC is appropriate therapy for patients in cardiogenic shock.
Study details
- Official title
- Arterial Compliance as a Predictor of Clinical Outcomes With Intra-aortic Balloon Counterpulsation: A Prospective Observational Pilot Study
- Sponsor
- Thomas Jefferson University
- Conditions
- Cardiogenic Shock · IABC Procedure · Intraaortic Balloon Counterpulsation (IABC)
- Enrolling
- 20 people
- Starts
- 2026-01-27
- Est. completion
- 2026-12-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Age ≥18 years old
- Cardiogenic shock
- Undergoing Intra-aortic Balloon Counterpulsation (IABC) as part of clinical care
- Able to provide consent or have power of attorney or next of kin provide consent
You can't join if
- Age <18 years old
- Unable to consent or does not have power of attorney or next of kin to consent
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openThomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States
- Elizabeth Westburg, MS · Contact267-872-1871elizabeth.westburg@jefferson.edu
- Matthew S Delfiner, DO, MS · Principal investigator
Recruiting
Study team
Sponsor
Thomas Jefferson University
Study ID 2025-0678
Principal investigator
Matthew S Delfiner, DO, MS
Thomas Jefferson University
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.