ORX489 tablets, single and repeated doses, in healthy adults aged 18 to 60

You may qualify if

• Healthy males or females as determined by assessments at the Screening Visit.
• For Parts A, B, C, and D:
• A. Participants must be at least 18 years of age and no more than 60 years of age at the Screening

You can't join if

• Presence of significant cardiac, pulmonary, gastrointestinal, hepatic, renal, hematological, malignancy, endocrine, neurological, or psychiatric disease, as determined by medical history, physical examination, and screening investigations.
• History of seizure disorder, any other condition that increases the risk of seizure 3. Has a clinically significant sleep disorder, including insomnia or sleep apnea.