What this study is
This study will examine the efficacy of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) compared to standard care among cancer survivors who smoke cigarettes and engage in at-risk alcohol use. Investigators will evaluate implementation outcomes through structured stakeholder interviews across medical centers, cancer-focused organizations, and community-based programs in Florida, and will conduct a cost-assessment and an incremental cost-effectiveness analysis of the two conditions.
What's being tested
- Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA)
Intervention · BEHAVIORAL
MBRP-SA is a nine-week, group-based mindfulness program designed to help cancer survivors quit smoking and reduce heavy alcohol use by targeting craving, stress, and habitual behavior patterns. Participants will also receive 10 weeks of nicotine replacement therapy.
- Quitline Support
Intervention · BEHAVIORAL
Participants will be connected to the Florida Tobacco Quitline, which provides standard evidence-based smoking cessation support, including phone-based counseling, web-based resources, and access to text-messaging programs. The Quitline also offers up to a four-week supply of nicotine replacement therapy (patches, gum, or lozenges). Participants will also receive referrals to various alcohol-related treatment options in the community.
Study details
- Official title
- Smoking Cessation and Alcohol Use Among Cancer Survivors: Investigating the Efficacy of a Mindfulness-Based Intervention
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
- Conditions
- Smoking Cessation · Alcohol Use
- Enrolling
- 600 people
- Starts
- 2026-05-15
- Est. completion
- 2029-12
- Design
- Open-label, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers AcceptedYou may qualify if
- ≥18 years old
- History of a cancer diagnosis at any point in lifetime
- Smoked ≥1 cigarette/day in past month
- At least one binge drinking episode in past month or exceeds weekly drinking limits
- Motivated to quit smoking and modify alcohol use in next 30 days
- Valid home address in Florida
- English-speaking, reading, and writing ability
You can't join if
- Pregnancy or lactation
- Active psychotic disorder
- History of severe alcohol withdrawal
- Current use of tobacco cessation medication or other treatments to quit smoking
- End-of-life or hospice care
- Household member already enrolled
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openMoffitt Cancer Center
Tampa, Florida, United States
- Christine Vinci, PhD · Principal investigator
- Vani Simmons, PhD · Sub-investigator
- Steve Sutton, PhD · Sub-investigator
- Margaret Byrne, PhD · Sub-investigator
- Kea Turner, PhD · Sub-investigator
- Katie Witkiewitz, PhD · Sub-investigator
Recruiting
Study team
Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Study ID MCC-23894
Principal investigator
Christine Vinci, PhD
Moffitt Cancer Center
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.