What this study is
This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend a HABIT-ILE + FST summer camp for 6 hours per day over a 3-week period, totaling 90 hours of training.
What's being tested
- Combined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FST)
Intervention · OTHER
Goal-directed, task-specific training for both the upper and lower extremity, and postural control with targeted strengthening exercises to enhance motor control and facilitate the achievement of functional goals
Study details
- Official title
- Feasibility and Preliminary Effectiveness of HABIT-ILE + Functional Strength Training in Children With Spinal Muscular Atrophy (SMA): a Prospective Single-group Intervention Trial.
- Sponsor
- Teachers College, Columbia University
- Conditions
- Spinal Muscular Atrophy (SMA)
- Enrolling
- 20 people
- Starts
- 2026-03-15
- Est. completion
- 2028-12-31
- Design
- Open-label, single group
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 5 Years – 17 YearsSex ALLHealthy volunteers Not acceptedYou may qualify if
- Have a confirmed SMA diagnosis
- Be 5-17 years old
- Complete all pre- and post-intervention assessments
- Understand and speak English
- Follow instructions without major cognitive or behavioral issues
- Have received a stable disease-modifying therapy (DMT) dose for ≥6 months
- Be classified as a sitter or walker (SMA type 2 or 3) with supported standing ability (score ≥1 on Item 18 of the HFMSE) without KAFOs, AFOs, or external standing devices
You can't join if
- Orthopedic surgery within the past year
- New pharmaceutical treatment during the study
- Concurrent participation in another clinical trial
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openCenter for Cerebral Palsy Research, Teachers College, Columbia University
New York, New York, United States
- Astrid Carton de Tournai, PhD · Contact(212) 678-3332cpresearch@tc.columbia.edu
Recruiting
Study team
Sponsor
Teachers College, Columbia University
Study ID 25-429-2
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.