What this study is
This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long. Specifically, the study aims to determine whether regular use of Lacrifill over a 2-3 month period can help people wear their contacts longer without discomfort and reduce signs and symptoms of dry eye.
What's being tested
- Lacrifill
Intervention · DRUG
Lacrifill is a cross-linked hyaluronic acid derivative that temporarily blocks tear drainage, allowing patients eyed to be bathed in their own natural tears.
Study details
- Official title
- Prospective, Single Arm Clinical Trial for the Treatment of Dry Eyes Signs and Symptoms in Patients With Limited Tolerability of Contact Lens Wear
- Sponsor
- Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists
- Conditions
- Dry Eye
- Enrolling
- 30 people
- Starts
- 2025-12-12
- Est. completion
- 2026-08
- Design
- Open-label, single group, Phase 4
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 22 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- >21 years of age
- Contact lens wearer
- Previous Dry Eye Treatment
- Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
- Schrimers Anesthetized less than or equal to 10
- CLDEQ-8 greater than or equal to 12
- Corneal Staining NEI grading scale greater than or equal to 1
You can't join if
- Known allergy to Hyaluronic Acid
- Current topical ophthalmic drops other than dry eye treatment
- Uncontrolled Diabetes
- Diabetic Retinopathy
- Pregnancy or Lactating
- Corneal Surgery (except Refractive)
- Corneal Scars
- Keratoconus
- Ocular Herpetic Keratitis
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openEye Care Specialists
Kingston, Pennsylvania, United States
- Patti Myers · Contact877-489-7405patti.myers@vipeyes.com
Recruiting
Study team
Sponsor
Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists
Study ID LAC-IST-001
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.