What this study is
High-achieving academic and entrepreneurial populations face elevated risks of chronic stress, anxiety, and burnout. These populations often underutilize mental health services due to stigma, time constraints, or accessibility issues. Digital interventions provide an opportunity to deliver evidence-based stress and resilience support at scale.
The WONE (Walking on Earth, Ltd.) platform integrates personalized stress-resilience assessments, behavioral science micro-interventions, and optional wearable data feedback. This project aims to evaluate the feasibility, engagement, and preliminary efficacy of the WONE digital intervention in multiple Stanford-affiliated cohorts.
What's being tested
- Intervention WONE App (full Version)
Intervention · BEHAVIORAL
The Intervention WONE app (Full version) has the following features: * AI coaching for personalized support * Educational articles * Live sessions * On-demand session recordings * WONE Index assessment and tracking * Wearable device connection (optional) and wearable-derived scores and metrics The control WONE app (limited version) has no above features, only has push notifications for participants to complete assessments.
Study details
- Official title
- Evaluating a Digital Intervention to Improve Resilience and Reduce Stress in Stanford Populations (SIER Study)
- Sponsor
- Stanford University
- Conditions
- Resilience, Psychological · Mental Well-being
- Enrolling
- 260 people
- Starts
- 2026-05
- Est. completion
- 2027-08
- Design
- Single-blind, randomized, crossover
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years – 65 YearsSex ALLHealthy volunteers AcceptedYou may qualify if
- Aged between 18 and 65 years with Stanford affiliation
- English proficiency with the ability to read, write, and complete surveys in English
- Smartphone with internet access
- Willingness to complete surveys and app activities
- Resides in the US
- Stanford affiliation
- Wearable device for Phase 1 Pilot Study
You can't join if
- Severe psychiatric instability, defined as any of the following self-reported on the pre-enrollment screener:; Psychiatric hospitalization for a mental health crisis in the past 12 months.; Current mental health symptoms that significantly impair ability to function in daily life (e.g., unable to work, attend school, or care for basic needs).
- No smartphone or unwilling to consent.
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openStanford School of Medicine
Stanford, California, United States
Study team
Sponsor
Stanford University
Study ID 84749
Principal investigator
Alan Yeung, MD
Stanford University
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.